Bioinspired Heterocoordination in Adaptable Cobalt Metal–Organic Framework for DNA Epigenetic Modification Detection

Metal–organic frameworks (MOFs) show unique advantages in simulating the dynamics and fidelity of natural coordination. Inspired by zinc finger protein, a second linker was introduced to affect the homogeneous MOF system and thus facilitate the emergence of diverse functionalities. Under the systema...

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Veröffentlicht in:	Analytical chemistry (Washington) 2024-06, Vol.96 (24), p.9984-9993
Hauptverfasser:	Wei, Zhongyu, Yu, Long, Feng, Yumin, Gan, Zhiwen, Shen, Yongjin, Peng, Shuang, Xiao, Yuxiu
Format:	Artikel
Sprache:	eng
Schlagworte:	5-Methylcytosine - analogs & derivatives 5-Methylcytosine - analysis 5-Methylcytosine - chemistry analytical chemistry Carbon dioxide Carboxylation Cobalt Cobalt - chemistry Coordination coordination polymers Cytosine - analogs & derivatives Cytosine - chemistry Deoxyribonucleic acid disease diagnosis Dissipation DNA DNA - chemistry Epigenesis, Genetic Epigenetics Information processing Introduced species Limit of Detection Metal ions Metal-organic frameworks Metal-Organic Frameworks - chemistry Nitrogen dioxide o-Phenylenediamine Phenylenediamine Phenylenediamines - chemistry Signal transduction species zinc finger motif Zinc finger proteins
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