Behavioral toxicity of TDCPP in marine zooplankton: Evidence from feeding and swimming responses, molecular dynamics and metabolomics of rotifers

As new organic flame retardants, chlorinated organophosphate esters (Cl-OPEs) have high water solubility and structural similarity to organophosphate pesticides, posing risks to aquatic organisms. The potential neurotoxicity of Cl-OPEs has attracted attention, especially in marine invertebrates with...

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Veröffentlicht in:	The Science of the total environment 2024-04, Vol.921, p.170864-170864, Article 170864
Hauptverfasser:	Zhang, Xin, Tong, Xin, Tang, Xuexi, Yang, Yixin, Zhang, Luyuchen, Zhan, Xiaotong, Zhang, Xinxin
Format:	Artikel
Sprache:	eng
Schlagworte:	acetylcholine AChE active sites Adenosine Triphosphate Animals Brachionus plicatilis Ceramides Chlorinated organophosphate esters electron transport chain energy environment fatty acid composition filtration Flame Retardants - toxicity fumonisins ganglia gangliosides gene expression regulation hydrogen bonding ingestion innervation Lipids Marine invertebrates membrane potential metabolites metabolomics mitochondria mitochondrial membrane Molecular Docking Simulation molecular dynamics Molecular Dynamics Simulation Neurotoxicity Organophosphates - toxicity organophosphorus compounds Organophosphorus Compounds - toxicity phosphates population growth reproduction Sphingolipid metabolism sphingosine N-acyltransferase Swimming tricarboxylic acid cycle unsaturated fatty acids van der Waals forces water solubility Zooplankton
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