Aza-Prilezhaev Aziridination-Enabled Multidimensional Analysis of Isomeric Lipids via High-Resolution U‑Shaped Mobility Analyzer–Mass Spectrometry

Unsaturated lipids constitute a significant portion of the lipidome, serving as players of multifaceted functions involving cellular signaling, membrane structure, and bioenergetics. While derivatization-assisted liquid chromatography tandem mass spectrometry (LC-MS/MS) remains the gold standard tec...

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Veröffentlicht in:	Analytical chemistry (Washington) 2024-05, Vol.96 (18), p.7111-7119
Hauptverfasser:	Li, Yuling, Wang, Yiming, Guo, Kang, Tseng, Kuo-feng, Zhang, Xiaoqiang, Sun, Wenjian
Format:	Artikel
Sprache:	eng
Schlagworte:	analytical chemistry Bioenergetics Carbon Cellular structure Depth profiling detection limit energy metabolism ethyleneimine geometry Ionic mobility Isomerization Isomers lipidomics Lipids Liquid chromatography Mass spectrometry Mass spectroscopy Membrane structure Membrane structures Mobility Position (location) Scientific imaging Sensitivity Side reactions tandem mass spectrometry
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