Juvenile hormone inhibits adult cuticle formation in Drosophila melanogaster through Kr‐h1/Dnmt2‐mediated DNA methylation of Acp65A promoter

Differentiation of imaginal epidermal cells of Drosophila melanogaster to form adult cuticles occurs at approximately 40–93 h after puparium formation. Juvenile hormone (JH) given at pupariation results in formation of a second pupal cuticle in the abdomen instead of the adult cuticle. Although the...

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Veröffentlicht in:	Insect molecular biology 2024-04, Vol.33 (2), p.124-135
Hauptverfasser:	He, Qianyu, Fan, Xiaochun, Wang, Shunxin, Chen, Shanshan, Chen, Jinxia
Format:	Artikel
Sprache:	eng
Schlagworte:	Abdomen Acp65A adult cuticle adults Binding sites Cell differentiation Deoxyribonucleic acid DNA DNA methylation DNA methyltransferase Drosophila melanogaster Epicuticle Fruit flies Gene sequencing genes Insects juvenile hormone Juvenile hormones Kr‐h1 Metamorphosis molecular biology Nucleotide sequence promoter regions pupae Pupariation puparium Regulatory mechanisms (biology)
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