Effects of the apricot diets containing sulfur dioxide at different concentrations on rat testicles
Due to its antioxidant and antimicrobial properties, sulfur dioxide (SO 2 ) is widely used in foods and beverages to prevent the growth of microorganisms and to preserve the color and flavor of fruits. However, the amount of SO 2 used in fruit preservation should be limited due to its possible adver...
Gespeichert in:
| Veröffentlicht in: | Environmental science and pollution research international 2023-06, Vol.30 (29), p.74301-74313 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 74313 |
|---|---|
| container_issue | 29 |
| container_start_page | 74301 |
| container_title | Environmental science and pollution research international |
| container_volume | 30 |
| creator | Yildiz, Azibe Ozhan, Onural Ulu, Ahmet Dogan, Tugba Bakar, Busra Ugur, Yilmaz Taslidere, Elif Gokbulut, Incilay Polat, Seyhan Parlakpinar, Hakan Ates, Burhan Vardi, Nigar |
| description | Due to its antioxidant and antimicrobial properties, sulfur dioxide (SO
2
) is widely used in foods and beverages to prevent the growth of microorganisms and to preserve the color and flavor of fruits. However, the amount of SO
2
used in fruit preservation should be limited due to its possible adverse effects on human health. The present study was designed to investigate the effects of different SO
2
concentrations in apricot diets on rat testes. Animals were randomly divided into six groups. The control group was fed a standard diet, and the other groups were fed apricot diet pellets prepared with (w/w) 10% dried apricots containing SO
2
at different concentrations (1500 ppm, 2000 ppm, 2500 ppm, 3000 ppm, and 3500 ppm/kg) for 24 weeks. After sacrification, testicles were evaluated biochemically, histopathologically, and immunohistopathologically. Our results showed that an apricot diet containing 1500 ppm and 2000 ppm SO
2
did not cause significant changes in testis. However, it was determined that tissue testosterone levels decreased as the amount of SO
2
(2500 ppm and above) increased. Apricot diet containing 3500 ppm SO
2
caused a significant increase in spermatogenic cell apoptosis, oxidative damage, and histopathological changes. In addition, a decrease in the expression of connexin-43, vimentin, and 3β-hydroxysteroid dehydrogenase (3β-HSD) was observed in the same group. In summary, the results show that sulfurization of apricot at high concentrations such as 3500 ppm may lead to male fertility problems in the long term through mechanisms such as oxidative stress, spermatogenic cell apoptosis, and inhibition of steroidogenesis. |
| doi_str_mv | 10.1007/s11356-023-27692-w |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_3153200498</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2816766075</sourcerecordid><originalsourceid>FETCH-LOGICAL-c408t-b43f82b14a073f50c1337fa5ba8a75a902527337c39a70410c54e5a3ea6035d23</originalsourceid><addsrcrecordid>eNqFkUlLBDEQhYMo7n_AgzR48dJa2TrdR5FxAcGLnkMmk2hLT6JJGvXfW-O44UFPVVS-94rKI2SPwhEFUMeZUi6bGhivmWo6Vj-vkE3aUFEr0XWrP_oNspXzAwCDjql1ssEVAyFVu0nsxHtnS66ir8q9q8xj6m0s1ax3OLQxFNOHPtxVeRz8mHAeX_oZcgsEpcmFssAs1mRKHwNahQrbqrhceju4vEPWvBmy2_2o2-T2bHJzelFfXZ9fnp5c1VZAW-qp4L5lUyoMKO4lWMq58kZOTWuUNB0wyRSOLO-MAkHBSuGk4c40wOWM8W1yuPR9TPFpxO163mfrhsEEF8esOZWcAYiu_RdlLW1U04CSiB78Qh_imAIeghRrpWgFp0ixJWVTzDk5r_Ej5ya9agp6kZZepqUxLf2eln5G0f6H9Tidu9mX5DMeBPgSyPgU7lz63v2H7RuRTZ-s</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2828548431</pqid></control><display><type>article</type><title>Effects of the apricot diets containing sulfur dioxide at different concentrations on rat testicles</title><source>SpringerLink Journals</source><creator>Yildiz, Azibe ; Ozhan, Onural ; Ulu, Ahmet ; Dogan, Tugba ; Bakar, Busra ; Ugur, Yilmaz ; Taslidere, Elif ; Gokbulut, Incilay ; Polat, Seyhan ; Parlakpinar, Hakan ; Ates, Burhan ; Vardi, Nigar</creator><creatorcontrib>Yildiz, Azibe ; Ozhan, Onural ; Ulu, Ahmet ; Dogan, Tugba ; Bakar, Busra ; Ugur, Yilmaz ; Taslidere, Elif ; Gokbulut, Incilay ; Polat, Seyhan ; Parlakpinar, Hakan ; Ates, Burhan ; Vardi, Nigar</creatorcontrib><description>Due to its antioxidant and antimicrobial properties, sulfur dioxide (SO
2
) is widely used in foods and beverages to prevent the growth of microorganisms and to preserve the color and flavor of fruits. However, the amount of SO
2
used in fruit preservation should be limited due to its possible adverse effects on human health. The present study was designed to investigate the effects of different SO
2
concentrations in apricot diets on rat testes. Animals were randomly divided into six groups. The control group was fed a standard diet, and the other groups were fed apricot diet pellets prepared with (w/w) 10% dried apricots containing SO
2
at different concentrations (1500 ppm, 2000 ppm, 2500 ppm, 3000 ppm, and 3500 ppm/kg) for 24 weeks. After sacrification, testicles were evaluated biochemically, histopathologically, and immunohistopathologically. Our results showed that an apricot diet containing 1500 ppm and 2000 ppm SO
2
did not cause significant changes in testis. However, it was determined that tissue testosterone levels decreased as the amount of SO
2
(2500 ppm and above) increased. Apricot diet containing 3500 ppm SO
2
caused a significant increase in spermatogenic cell apoptosis, oxidative damage, and histopathological changes. In addition, a decrease in the expression of connexin-43, vimentin, and 3β-hydroxysteroid dehydrogenase (3β-HSD) was observed in the same group. In summary, the results show that sulfurization of apricot at high concentrations such as 3500 ppm may lead to male fertility problems in the long term through mechanisms such as oxidative stress, spermatogenic cell apoptosis, and inhibition of steroidogenesis.</description><identifier>ISSN: 1614-7499</identifier><identifier>ISSN: 0944-1344</identifier><identifier>EISSN: 1614-7499</identifier><identifier>DOI: 10.1007/s11356-023-27692-w</identifier><identifier>PMID: 37204578</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>17-beta-hydroxysteroid dehydrogenase ; antioxidants ; Apoptosis ; Apricots ; Aquatic Pollution ; Atmospheric Protection/Air Quality Control/Air Pollution ; Beverages ; color ; Connexin 43 ; Diet ; Earth and Environmental Science ; Ecotoxicology ; Environment ; Environmental Chemistry ; Environmental Health ; Environmental science ; Fertility ; flavor ; Fruits ; histopathology ; human health ; Hydroxysteroids ; male fertility ; Microorganisms ; Oxidative stress ; rats ; Research Article ; Steroidogenesis ; Sulfur ; Sulfur dioxide ; Sulfurization ; Testes ; Testosterone ; Vimentin ; Waste Water Technology ; Water Management ; Water Pollution Control</subject><ispartof>Environmental science and pollution research international, 2023-06, Vol.30 (29), p.74301-74313</ispartof><rights>The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.</rights><rights>2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c408t-b43f82b14a073f50c1337fa5ba8a75a902527337c39a70410c54e5a3ea6035d23</citedby><cites>FETCH-LOGICAL-c408t-b43f82b14a073f50c1337fa5ba8a75a902527337c39a70410c54e5a3ea6035d23</cites><orcidid>0000-0001-5686-7867</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s11356-023-27692-w$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s11356-023-27692-w$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/37204578$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Yildiz, Azibe</creatorcontrib><creatorcontrib>Ozhan, Onural</creatorcontrib><creatorcontrib>Ulu, Ahmet</creatorcontrib><creatorcontrib>Dogan, Tugba</creatorcontrib><creatorcontrib>Bakar, Busra</creatorcontrib><creatorcontrib>Ugur, Yilmaz</creatorcontrib><creatorcontrib>Taslidere, Elif</creatorcontrib><creatorcontrib>Gokbulut, Incilay</creatorcontrib><creatorcontrib>Polat, Seyhan</creatorcontrib><creatorcontrib>Parlakpinar, Hakan</creatorcontrib><creatorcontrib>Ates, Burhan</creatorcontrib><creatorcontrib>Vardi, Nigar</creatorcontrib><title>Effects of the apricot diets containing sulfur dioxide at different concentrations on rat testicles</title><title>Environmental science and pollution research international</title><addtitle>Environ Sci Pollut Res</addtitle><addtitle>Environ Sci Pollut Res Int</addtitle><description>Due to its antioxidant and antimicrobial properties, sulfur dioxide (SO
2
) is widely used in foods and beverages to prevent the growth of microorganisms and to preserve the color and flavor of fruits. However, the amount of SO
2
used in fruit preservation should be limited due to its possible adverse effects on human health. The present study was designed to investigate the effects of different SO
2
concentrations in apricot diets on rat testes. Animals were randomly divided into six groups. The control group was fed a standard diet, and the other groups were fed apricot diet pellets prepared with (w/w) 10% dried apricots containing SO
2
at different concentrations (1500 ppm, 2000 ppm, 2500 ppm, 3000 ppm, and 3500 ppm/kg) for 24 weeks. After sacrification, testicles were evaluated biochemically, histopathologically, and immunohistopathologically. Our results showed that an apricot diet containing 1500 ppm and 2000 ppm SO
2
did not cause significant changes in testis. However, it was determined that tissue testosterone levels decreased as the amount of SO
2
(2500 ppm and above) increased. Apricot diet containing 3500 ppm SO
2
caused a significant increase in spermatogenic cell apoptosis, oxidative damage, and histopathological changes. In addition, a decrease in the expression of connexin-43, vimentin, and 3β-hydroxysteroid dehydrogenase (3β-HSD) was observed in the same group. In summary, the results show that sulfurization of apricot at high concentrations such as 3500 ppm may lead to male fertility problems in the long term through mechanisms such as oxidative stress, spermatogenic cell apoptosis, and inhibition of steroidogenesis.</description><subject>17-beta-hydroxysteroid dehydrogenase</subject><subject>antioxidants</subject><subject>Apoptosis</subject><subject>Apricots</subject><subject>Aquatic Pollution</subject><subject>Atmospheric Protection/Air Quality Control/Air Pollution</subject><subject>Beverages</subject><subject>color</subject><subject>Connexin 43</subject><subject>Diet</subject><subject>Earth and Environmental Science</subject><subject>Ecotoxicology</subject><subject>Environment</subject><subject>Environmental Chemistry</subject><subject>Environmental Health</subject><subject>Environmental science</subject><subject>Fertility</subject><subject>flavor</subject><subject>Fruits</subject><subject>histopathology</subject><subject>human health</subject><subject>Hydroxysteroids</subject><subject>male fertility</subject><subject>Microorganisms</subject><subject>Oxidative stress</subject><subject>rats</subject><subject>Research Article</subject><subject>Steroidogenesis</subject><subject>Sulfur</subject><subject>Sulfur dioxide</subject><subject>Sulfurization</subject><subject>Testes</subject><subject>Testosterone</subject><subject>Vimentin</subject><subject>Waste Water Technology</subject><subject>Water Management</subject><subject>Water Pollution Control</subject><issn>1614-7499</issn><issn>0944-1344</issn><issn>1614-7499</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>BENPR</sourceid><recordid>eNqFkUlLBDEQhYMo7n_AgzR48dJa2TrdR5FxAcGLnkMmk2hLT6JJGvXfW-O44UFPVVS-94rKI2SPwhEFUMeZUi6bGhivmWo6Vj-vkE3aUFEr0XWrP_oNspXzAwCDjql1ssEVAyFVu0nsxHtnS66ir8q9q8xj6m0s1ax3OLQxFNOHPtxVeRz8mHAeX_oZcgsEpcmFssAs1mRKHwNahQrbqrhceju4vEPWvBmy2_2o2-T2bHJzelFfXZ9fnp5c1VZAW-qp4L5lUyoMKO4lWMq58kZOTWuUNB0wyRSOLO-MAkHBSuGk4c40wOWM8W1yuPR9TPFpxO163mfrhsEEF8esOZWcAYiu_RdlLW1U04CSiB78Qh_imAIeghRrpWgFp0ixJWVTzDk5r_Ej5ya9agp6kZZepqUxLf2eln5G0f6H9Tidu9mX5DMeBPgSyPgU7lz63v2H7RuRTZ-s</recordid><startdate>20230601</startdate><enddate>20230601</enddate><creator>Yildiz, Azibe</creator><creator>Ozhan, Onural</creator><creator>Ulu, Ahmet</creator><creator>Dogan, Tugba</creator><creator>Bakar, Busra</creator><creator>Ugur, Yilmaz</creator><creator>Taslidere, Elif</creator><creator>Gokbulut, Incilay</creator><creator>Polat, Seyhan</creator><creator>Parlakpinar, Hakan</creator><creator>Ates, Burhan</creator><creator>Vardi, Nigar</creator><general>Springer Berlin Heidelberg</general><general>Springer Nature B.V</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QL</scope><scope>7SN</scope><scope>7T7</scope><scope>7TV</scope><scope>7U7</scope><scope>7WY</scope><scope>7WZ</scope><scope>7X7</scope><scope>7XB</scope><scope>87Z</scope><scope>88E</scope><scope>88I</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8FL</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BEZIV</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FRNLG</scope><scope>FYUFA</scope><scope>F~G</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K60</scope><scope>K6~</scope><scope>K9.</scope><scope>L.-</scope><scope>M0C</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>M7N</scope><scope>P64</scope><scope>PATMY</scope><scope>PQBIZ</scope><scope>PQBZA</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PYCSY</scope><scope>Q9U</scope><scope>7X8</scope><scope>7S9</scope><scope>L.6</scope><orcidid>https://orcid.org/0000-0001-5686-7867</orcidid></search><sort><creationdate>20230601</creationdate><title>Effects of the apricot diets containing sulfur dioxide at different concentrations on rat testicles</title><author>Yildiz, Azibe ; Ozhan, Onural ; Ulu, Ahmet ; Dogan, Tugba ; Bakar, Busra ; Ugur, Yilmaz ; Taslidere, Elif ; Gokbulut, Incilay ; Polat, Seyhan ; Parlakpinar, Hakan ; Ates, Burhan ; Vardi, Nigar</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c408t-b43f82b14a073f50c1337fa5ba8a75a902527337c39a70410c54e5a3ea6035d23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>17-beta-hydroxysteroid dehydrogenase</topic><topic>antioxidants</topic><topic>Apoptosis</topic><topic>Apricots</topic><topic>Aquatic Pollution</topic><topic>Atmospheric Protection/Air Quality Control/Air Pollution</topic><topic>Beverages</topic><topic>color</topic><topic>Connexin 43</topic><topic>Diet</topic><topic>Earth and Environmental Science</topic><topic>Ecotoxicology</topic><topic>Environment</topic><topic>Environmental Chemistry</topic><topic>Environmental Health</topic><topic>Environmental science</topic><topic>Fertility</topic><topic>flavor</topic><topic>Fruits</topic><topic>histopathology</topic><topic>human health</topic><topic>Hydroxysteroids</topic><topic>male fertility</topic><topic>Microorganisms</topic><topic>Oxidative stress</topic><topic>rats</topic><topic>Research Article</topic><topic>Steroidogenesis</topic><topic>Sulfur</topic><topic>Sulfur dioxide</topic><topic>Sulfurization</topic><topic>Testes</topic><topic>Testosterone</topic><topic>Vimentin</topic><topic>Waste Water Technology</topic><topic>Water Management</topic><topic>Water Pollution Control</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Yildiz, Azibe</creatorcontrib><creatorcontrib>Ozhan, Onural</creatorcontrib><creatorcontrib>Ulu, Ahmet</creatorcontrib><creatorcontrib>Dogan, Tugba</creatorcontrib><creatorcontrib>Bakar, Busra</creatorcontrib><creatorcontrib>Ugur, Yilmaz</creatorcontrib><creatorcontrib>Taslidere, Elif</creatorcontrib><creatorcontrib>Gokbulut, Incilay</creatorcontrib><creatorcontrib>Polat, Seyhan</creatorcontrib><creatorcontrib>Parlakpinar, Hakan</creatorcontrib><creatorcontrib>Ates, Burhan</creatorcontrib><creatorcontrib>Vardi, Nigar</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Ecology Abstracts</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Pollution Abstracts</collection><collection>Toxicology Abstracts</collection><collection>ABI/INFORM Collection</collection><collection>ABI/INFORM Global (PDF only)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>ABI/INFORM Global (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Technology Research Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ABI/INFORM Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>Business Premium Collection</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Business Premium Collection (Alumni)</collection><collection>Health Research Premium Collection</collection><collection>ABI/INFORM Global (Corporate)</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Business Collection (Alumni Edition)</collection><collection>ProQuest Business Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ABI/INFORM Professional Advanced</collection><collection>ABI/INFORM Global</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Environmental Science Database</collection><collection>ProQuest One Business</collection><collection>ProQuest One Business (Alumni)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>Environmental Science Collection</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>AGRICOLA</collection><collection>AGRICOLA - Academic</collection><jtitle>Environmental science and pollution research international</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Yildiz, Azibe</au><au>Ozhan, Onural</au><au>Ulu, Ahmet</au><au>Dogan, Tugba</au><au>Bakar, Busra</au><au>Ugur, Yilmaz</au><au>Taslidere, Elif</au><au>Gokbulut, Incilay</au><au>Polat, Seyhan</au><au>Parlakpinar, Hakan</au><au>Ates, Burhan</au><au>Vardi, Nigar</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effects of the apricot diets containing sulfur dioxide at different concentrations on rat testicles</atitle><jtitle>Environmental science and pollution research international</jtitle><stitle>Environ Sci Pollut Res</stitle><addtitle>Environ Sci Pollut Res Int</addtitle><date>2023-06-01</date><risdate>2023</risdate><volume>30</volume><issue>29</issue><spage>74301</spage><epage>74313</epage><pages>74301-74313</pages><issn>1614-7499</issn><issn>0944-1344</issn><eissn>1614-7499</eissn><abstract>Due to its antioxidant and antimicrobial properties, sulfur dioxide (SO
2
) is widely used in foods and beverages to prevent the growth of microorganisms and to preserve the color and flavor of fruits. However, the amount of SO
2
used in fruit preservation should be limited due to its possible adverse effects on human health. The present study was designed to investigate the effects of different SO
2
concentrations in apricot diets on rat testes. Animals were randomly divided into six groups. The control group was fed a standard diet, and the other groups were fed apricot diet pellets prepared with (w/w) 10% dried apricots containing SO
2
at different concentrations (1500 ppm, 2000 ppm, 2500 ppm, 3000 ppm, and 3500 ppm/kg) for 24 weeks. After sacrification, testicles were evaluated biochemically, histopathologically, and immunohistopathologically. Our results showed that an apricot diet containing 1500 ppm and 2000 ppm SO
2
did not cause significant changes in testis. However, it was determined that tissue testosterone levels decreased as the amount of SO
2
(2500 ppm and above) increased. Apricot diet containing 3500 ppm SO
2
caused a significant increase in spermatogenic cell apoptosis, oxidative damage, and histopathological changes. In addition, a decrease in the expression of connexin-43, vimentin, and 3β-hydroxysteroid dehydrogenase (3β-HSD) was observed in the same group. In summary, the results show that sulfurization of apricot at high concentrations such as 3500 ppm may lead to male fertility problems in the long term through mechanisms such as oxidative stress, spermatogenic cell apoptosis, and inhibition of steroidogenesis.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>37204578</pmid><doi>10.1007/s11356-023-27692-w</doi><tpages>13</tpages><orcidid>https://orcid.org/0000-0001-5686-7867</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1614-7499 |
| ispartof | Environmental science and pollution research international, 2023-06, Vol.30 (29), p.74301-74313 |
| issn | 1614-7499 0944-1344 1614-7499 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_3153200498 |
| source | SpringerLink Journals |
| subjects | 17-beta-hydroxysteroid dehydrogenase antioxidants Apoptosis Apricots Aquatic Pollution Atmospheric Protection/Air Quality Control/Air Pollution Beverages color Connexin 43 Diet Earth and Environmental Science Ecotoxicology Environment Environmental Chemistry Environmental Health Environmental science Fertility flavor Fruits histopathology human health Hydroxysteroids male fertility Microorganisms Oxidative stress rats Research Article Steroidogenesis Sulfur Sulfur dioxide Sulfurization Testes Testosterone Vimentin Waste Water Technology Water Management Water Pollution Control |
| title | Effects of the apricot diets containing sulfur dioxide at different concentrations on rat testicles |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-15T10%3A53%3A19IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Effects%20of%20the%20apricot%20diets%20containing%20sulfur%20dioxide%20at%20different%20concentrations%20on%20rat%20testicles&rft.jtitle=Environmental%20science%20and%20pollution%20research%20international&rft.au=Yildiz,%20Azibe&rft.date=2023-06-01&rft.volume=30&rft.issue=29&rft.spage=74301&rft.epage=74313&rft.pages=74301-74313&rft.issn=1614-7499&rft.eissn=1614-7499&rft_id=info:doi/10.1007/s11356-023-27692-w&rft_dat=%3Cproquest_cross%3E2816766075%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2828548431&rft_id=info:pmid/37204578&rfr_iscdi=true |