Effects of quercetin on hepatic fibroblast growth factor-21 (FGF-21) and peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α) levels in rats fed with high fructose

Background Available studies show that quercetin reduces Metabolic Syndrome (MetS) and its complications, increases insulin sensitivity and improves glucose levels. It has been reported that the increase in hepatic gene expressions of fibroblast growth factor-21 (FGF-21), an important metabolic regu...

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Veröffentlicht in:	Molecular biology reports 2023-06, Vol.50 (6), p.4983-4997
Hauptverfasser:	Kocaman Kalkan, Kardelen, Şen, Serkan, Narlı, Belkıs, Seymen, Cemile Merve, Yılmaz, Canan
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal Anatomy Animal Biochemistry Animals Biomedical and Life Sciences Blood pressure blood serum Body weight Carbohydrate metabolism Cholesterol energy Energy balance Energy metabolism Fibroblast growth factors Fibroblast Growth Factors - metabolism Fibroblasts Fructose Fructose - metabolism Fructose - pharmacology genes Glucose Glucose - metabolism Growth factors High density lipoprotein Histology Homeostasis insulin Insulin Resistance Life Sciences Lipid metabolism Lipoproteins (very low density) Liver Liver - metabolism Male males messenger RNA Metabolic disorders Metabolic syndrome Metabolic Syndrome - metabolism Morphology mRNA Original Article peroxisome proliferator-activated receptor gamma Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha - genetics Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha - metabolism Peroxisome proliferator-activated receptors Quercetin Quercetin - metabolism Quercetin - pharmacology Rats Rats, Sprague-Dawley RNA, Messenger - metabolism therapeutics triacylglycerols very low density lipoprotein
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