Three new meroterpenoids from Sargassum macrocarpum and their inhibitory activity against amyloid β aggregation

Amyloid β (Aβ) is thought to be involved in the pathogenesis of Alzheimer’s disease (AD). Aβ aggregation in the brain is considered the cause of AD. Therefore, inhibiting Aβ aggregation and degrading existing Aβ aggregates is a promising approach for the treatment and prevention of the disease. In s...

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Veröffentlicht in:Journal of natural medicines 2023-06, Vol.77 (3), p.508-515
Hauptverfasser: Shinoda, Seiya, Tozawa, Yuta, Kurimoto, Shin-ichiro, Shigemori, Hideyuki, Sekiguchi, Mitsuhiro
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Sprache:eng
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