Talin mechanotransduction in disease

Talin protein (Talin 1/2) is a mechanosensitive cytoskeleton protein. The unique structure of the Talin plays a vital role in transmitting mechanical forces. Talin proteins connect the extracellular matrix to the cytoskeleton by linking to integrins and actin, thereby mediating the conversion of mec...

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Veröffentlicht in:	The international journal of biochemistry & cell biology 2024-01, Vol.166, p.106490-106490, Article 106490
Hauptverfasser:	Wang, Yingzi, Huang, Haozhong, Weng, Huimin, Jia, Chunsen, Liao, Bin, Long, Yang, Yu, Fengxu, Nie, Yongmei
Format:	Artikel
Sprache:	eng
Schlagworte:	actin Actins - metabolism Cell adhesion Cell Adhesion - physiology Cytoskeletal protein cytoskeleton Cytoskeleton - metabolism disease progression extracellular matrix integrins Integrins - metabolism Mechanical force mechanotransduction Mechanotransduction, Cellular Talin Talin - chemistry Talin - metabolism therapeutics
Online-Zugang:	Volltext
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