SGIV evades interferon immune response via the degradation of STING-TBK1 complex by VP149

Singapore grouper iridovirus (SGIV), a highly pathogenic member of iridoviruses, has become a global threat in the aquaculture industry due to its economic losses and damage to ecological diversity worldwide. Recent reports have shown that SGIV inhibits host interferon (IFN) immune response induced...

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Veröffentlicht in:	Aquaculture 2024-04, Vol.584, p.740666, Article 740666
Hauptverfasser:	Gao, Xiaolin, Lin, Long, Zhao, Yin, Wang, Yu, Yang, Xinmei, Liu, Shanxing, Huang, Xiaohong, Qin, Qiwei, Huang, Youhua, Zhang, Ya
Format:	Artikel
Sprache:	eng
Schlagworte:	aquaculture aquaculture industry Epinephelus coioides fish gene expression genes Immune evasion immune response interferon regulatory factor-3 interferons lysosomes melanoma mitochondria pathogenesis Redspotted grouper nervous necrosis virus SGIV Singapore grouper iridovirus STING TBK1 VP149
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