Biotransformation of betulin to betulinic acid by Fusarium lacertarum BRF59, an endophytic fungus isolated from the genus Betula

Betulinic acid (BA), a betulin derivative, is an important plant-based natural product. BA has many biological activities and attracts attention especially as a promising antitumour drug. Extraction from plants or semi-synthesis from betulin are the common methods to obtain BA, but these methods hav...

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