Differential processing of CRISPR RNA by LinCas5c and LinCas6 of Leptospira

Leptospira interrogans serovar Copenhageni's genome harbors two CRISPR-Cas systems belonging to subtypes IB and IC. However, in L. interrogans, the subtype IC locus lacks an array component essential for assembling an interference complex. Thus, the reason for sustaining the expense of a cluste...

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Veröffentlicht in:	Biochimica et biophysica acta. General subjects 2023-12, Vol.1867 (12), p.130469-130469, Article 130469
Hauptverfasser:	Anand, Vineet, Prabhakaran, Harshini Sheeja, Prakash, Aman, Hussain, Md Saddam, Kumar, Manish
Format:	Artikel
Sprache:	eng
Schlagworte:	bioinformatics Cas5 CRISPR sequences CRISPR-Cas I[sbnd]C CRISPR-Cas systems deoxyribonucleases functional diversity genome Leptospira Leptospira interrogans serovar Copenhageni LinCas5c loci mutants ribonucleases RNA
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