Polyethylenimine-functionalized fibroin nanoparticles as a potential oral delivery system for BCS class-IV drugs, a case study of furosemide

Limited studies have exploited the silk fibroin potential as an oral drug delivery system. Herein, this study developed and characterized the polyethylenimine-functionalized fibroin nanoparticles (PEI-FNP) and the FNP (as a reference), loaded with furosemide, a Biopharmaceutics Classification System...

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Veröffentlicht in:	Journal of materials science 2023-06, Vol.58 (23), p.9660-9674
Hauptverfasser:	Pham, Duy Toan, Nguyen, Thanh Lich, Nguyen, Thi Truc Linh, Nguyen, Thi Truc Phuong, Ho, Tuan Kiet, Nguyen, Ngoc Yen, Tran, Van De, Ha, Thi Kim Quy
Format:	Artikel
Sprache:	eng
Schlagworte:	Adsorption Analysis Bioavailability Case studies Characterization and Evaluation of Materials Chemistry and Materials Science Classical Mechanics Crystallography and Scattering Methods Drug delivery systems Drugs Entrapment fibroins Football (College) Furosemide hemolysis Infrared spectra intestines Materials for Life Sciences Materials Science Nanoparticles Polyethyleneimine Polymer Sciences Silk fibroin Solid Mechanics solubility stomach Sustained release Vehicles
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