Customized multi-stimuli nanovehicles with dissociable ‘bomblets’ for photothermal-enhanced synergetic tumor therapy

Recently, the therapeutic effect of chemotherapy has been obviously impaired due to premature drug release, low tumor penetration, and multidrug resistance of nanoplatforms. In this paper, a novel multiple-sensitive drug delivery system (MC-ss-CDs) was developed by gating long-wavelength emitting ca...

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Veröffentlicht in:	Colloids and surfaces, B, Biointerfaces B, Biointerfaces, 2023-02, Vol.222, p.113083, Article 113083
Hauptverfasser:	Lin, Jiayin, Li, Gang, Jiang, Ke, Xu, Tao, Liu, Chang, Wang, Lipin, Zhang, Xu, Cai, Defu, Wu, Chao, Meng, Xianshi, Zhu, Wenquan
Format:	Artikel
Sprache:	eng
Schlagworte:	bioimaging Carbon - chemistry carbon nanoparticles Cell Line, Tumor cytoplasm disulfides Disulfides - pharmacology doxorubicin Doxorubicin - chemistry drug delivery systems Drug Delivery Systems - methods Drug Liberation drug therapy heat Humans Improved permeability Mesoporous carbon nanoparticles multiple drug resistance Nanoparticles - chemistry neoplasms Neoplasms - drug therapy Neoplasms - pathology Phototherapy - methods Photothermal-enhanced synergistic therapy photothermotherapy porous media Red-light carbon dots Tumor Microenvironment Tumor-targeted
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