Macrocyclizing DNA-Linked Peptides via Three-Component Cyclization and Photoinduced Chemistry

While DNA-encoded macrocyclic libraries have gained substantial attention and several hit compounds have been identified from DNA-encoded library technology, efficient on-DNA macrocyclic methods are also required to construct DNA-linked libraries with a high degree of cyclization and DNA integrity....

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Veröffentlicht in:	Organic letters 2024-04, Vol.26 (14), p.2763-2767
Hauptverfasser:	Bao, Yandan, Xing, Minyan, Matthew, Naylor, Chen, Xiaohua, Wang, Xuan, Lu, Xiaojie
Format:	Artikel
Sprache:	eng
Schlagworte:	DNA peptides redox reactions
Online-Zugang:	Volltext
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