Shen-Ling-Bai-Zhu-San alleviates the imbalance of intestinal homeostasis in dextran sodium sulfate-induced colitis mice by regulating gut microbiota and inhibiting the NLRP3 inflammasome activation

Shen-Ling-Bai-Zhu-San (SLBZS) is a classic formula for strengthening the spleen and dispelling dampness, which has shown excellent efficacy in inflammatory bowel disease (IBD) in traditional Chinese medicine clinical studies. However, its exact pharmacological mechanism needs to be further elucidate...

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Veröffentlicht in:	Journal of ethnopharmacology 2024-01, Vol.319, p.117136-117136, Article 117136
Hauptverfasser:	Gao, Qianru, Tian, Weiyi, Yang, Huabing, Hu, Haiming, Zheng, Junping, Yao, Xiaowei, Hu, Baifei, Liu, Hongtao
Format:	Artikel
Sprache:	eng
Schlagworte:	agglutinins antibiotics body weight Colitis colon Coprococcus dextran sulfate fluorescein Gut microbiota homeostasis inflammasomes Intestinal homeostasis intestinal microorganisms mucins mucus NLRP3 inflammasome Oriental traditional medicine protein synthesis quantitative polymerase chain reaction secretion Shen-Ling-Bai-Zhu-San sodium spleen Western blotting wheat germ
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