Development and evaluation of a novel topically applied sildenafil citrate hydrogel and its influence on wound healing in dogs

OBJECTIVETo develop a topical sildenafil hydrogel and evaluate its effect on wound healing in dogs. ANIMALS6 purpose-bred, sexually intact, adult Beagles. PROCEDURESHydrogels containing sildenafil citrate, N-methyl-2-pyrrolidone, propylene glycol, and poloxamer 407 were developed. Four excision woun...

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Veröffentlicht in:	American journal of veterinary research 2022-08, Vol.83 (8)
Hauptverfasser:	Sumner, Scarlett M., Wallace, Mandy L., Mulder, Alan T., Delmotte, Sarah B., Duran, Sue H., Lindell, Heather, Annaji, Manjusha, Dimick, Tessa, Poudel, Ishwor, Babu, Jayachandra R.
Format:	Artikel
Sprache:	eng
Schlagworte:	adults ambient temperature angiogenesis bandages biopsy citrates excision granulation tissue histology hydrogels propylene glycol veterinary medicine
Online-Zugang:	Volltext
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