Magnesium peroxide-based biomimetic nanoigniter degrades extracellular matrix to awake T cell-mediated cancer immunotherapy

As the elite force of our immune system, T cells play a determining role in the effectiveness of cancer immunotherapy. However, the clever tumor cells construct a strong immunosuppressive tumor microenvironment (TME) fortress to resist the attack of T cells. Herein, a magnesium peroxide (MP)-based b...

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Veröffentlicht in:	Biomaterials 2025-06, Vol.317, p.123043, Article 123043
Hauptverfasser:	Hao, Huisong, Sun, Shengjie, Fu, Yanan, Wen, Simin, Wen, Yingfei, Yi, Yunfei, Peng, Zhangwen, Fang, Yixuan, Tang, Jia, Wang, Tianqi, Wu, Meiying
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomimetic nanomedicine Cancer therapy Magnesium peroxide Metalloimmunotherapy Tumor microenvironment
Online-Zugang:	Volltext
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