Prognostic implications and therapeutic opportunities related to CAF subtypes in CMS4 colorectal cancer: insights from single-cell and bulk transcriptomics

Cancer-associated fibroblasts (CAFs) significantly influence tumor progression and therapeutic resistance in colorectal cancer (CRC). However, the distributions and functions of CAF subpopulations vary across the four consensus molecular subtypes (CMSs) of CRC. This study performed single-cell RNA a...

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Veröffentlicht in:	Apoptosis (London) 2025-01
Hauptverfasser:	Ma, Mengke, Chu, Jin, Zhuo, Changhua, Xiong, Xin, Gu, Wenchao, Li, Hansheng, Xu, Midie, Huang, Dan
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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