Basic Science and Pathogenesis

The presence of Tau pathology is strongly associated with the clinical symptoms and cognitive decline found in Alzheimer's disease (AD), suggesting that targeting pathological tau may be a more effective therapeutic approach. Microglia have been implicated in tauopathies as their activation is...

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Veröffentlicht in:	Alzheimer's & dementia 2024-12, Vol.20 Suppl 1, p.e093442
Hauptverfasser:	Joers, Valerie L, Bagheri, Ila, Coronado, Jazmyn, Hillard, Cecilia, Tansey, Malu Gámez
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer Disease - genetics Alzheimer Disease - metabolism Alzheimer Disease - pathology Animals Brain - metabolism Brain - pathology Disease Models, Animal Humans Mice Mice, Knockout Mice, Transgenic Microglia - metabolism Organ Culture Techniques Phosphorylation Receptor, Cannabinoid, CB2 - genetics Receptor, Cannabinoid, CB2 - metabolism tau Proteins - metabolism Tauopathies - metabolism Tauopathies - pathology
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