Novel Naphthyridones Targeting Pannexin 1 for Colitis Management

Pannexin 1 (PANX1) forms cell-surface channels capable of releasing signaling metabolites for diverse patho-physiological processes. While inhibiting dysregulated PANX1 has been proposed as a therapeutic strategy for many pathological conditions, including inflammatory bowel disease (IBD), low effic...

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Veröffentlicht in:	Advanced science 2024-12, p.e2411538
Hauptverfasser:	Hsueh, Wen-Yun, Wu, Yi-Ling, Weng, Meng-Tzu, Liu, Shin-Yun, Santavanond, Jascinta P, Liu, Yi-Chung, Lin, Ching-I, Lai, Cheng-Nong, Lu, Yi-Ru, Hsu, Jing Yin, Gao, Hong-Yu, Lee, Jinq-Chyi, Wei, Shu-Chen, Lyu, Ping-Chiang, Poon, Ivan K H, Hsieh, Hsing-Pang, Chiu, Yu-Hsin
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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