Hypoxia-induced increase in sphingomyelin synthase 2 aggravates ischemic skeletal muscle inflammation

Critical limb ischemia (CLI) is the most advanced stage of peripheral arterial disease, posing a high risk of mortality. Sphingomyelin, a sphingolipid synthesized by sphingomyelin synthases (SMSs) 1 and 2, plays an essential role in signal transduction as a component of lipid rafts. However, the rol...

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Veröffentlicht in:	The FEBS journal 2024-12
Hauptverfasser:	Mizugaki, Hinano, Nagane, Masaki, Sato-Akaba, Hideo, Kmiec, Maciej, Kuppusamy, Periannan, Yasui, Hironobu, Inanami, Osamu, Murakami, Hironobu, Aihara, Naoyuki, Kamiie, Junichi, Mizunoya, Wataru, Yasuda, Ibuki, Fukuyama, Tomoki, Naya, Yuko, Yamashita, Tadashi
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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