PFOA substitute GenX at a sub-cytotoxic level exhibits thyroid-disrupting effects by inhibiting the expression of Thyroid Transcription Factor 1

While the occurrence of GenX, a novel alternative for perfluorooctanoic acid (PFOA), in the environment and its cytotoxicity at high concentrations to thyroid cells are well documented, limited information is available regarding its impact at low concentrations. GenX is detected to be as low as 0.00...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Environmental pollution (1987) 2024-12, Vol.367, p.125594, Article 125594
Hauptverfasser:	He, Shuangjun, Xie, Cuiying, Wang, Yu, Wang, Yaru, Fan, Chenyu, Su, Shu, Qian, Mingping, Yang, Yipeng
Format:	Artikel
Sprache:	eng
Schlagworte:	GenX hexafluoropropylene-oxide-dimer-acid Thyroid disruption thyroid transcription factor 1 Wnt/β-catenin pathway
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!