Probing the interaction mechanism of tigecycline with γ-globulin and hemoglobin in the absence and presence of amikacin

The interaction mechanism of tigecycline with γ-globulin and hemoglobin in the absence and presence of amikacin was investigated through multipectral, molecular docking and molecular dynamics simulation. The results show that tigecycline and γ-globulin/hemoglobin forms a ground state complex without...

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Veröffentlicht in:	International journal of biological macromolecules 2025-02, Vol.291, p.139109, Article 139109
Hauptverfasser:	Li, Xiangrong, Zhao, Jingjing, Liu, Xianfei, Song, Zhizhi, Xu, Wanqing, Li, Zheng
Format:	Artikel
Sprache:	eng
Schlagworte:	Ternary system The interaction mechanism Tigecycline
Online-Zugang:	Volltext
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