Liver Kinase B1 Protects Against Hypoxia-Induced Pulmonary Arterial Endothelial Cell Dysfunction via the AMP-Activated Protein Kinase Pathway

Pulmonary hypertension (PH) is a progressive disease characterized by vascular reHypoxiaing, endothelial cell dysfunction, and inflammation. Liver Kinase B1 (LKB1, also known as STK11) is a central regulator of cell polarity and energy homeostasis. However, its specific role and mechanism of action...

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Veröffentlicht in:	Biochemical genetics 2024-12
Hauptverfasser:	Hei, Bingchang, Zhang, Anzhe, Yang, Meiming, Jiang, Yunfei, Guan, Zhanjiang
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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