Metabolic Reprogramming of Macrophages by Biomimetic Melatonin-Loaded Liposomes Effectively Attenuates Acute Gouty Arthritis in a Mouse Model

Gouty arthritis is characterized by an acute inflammatory response triggered by monosodium urate (MSU) crystals deposited in the joints and periarticular tissues. Current treatments bring little effects owing to serious side effects, necessitating the exploration of new and safer therapeutic options...

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Veröffentlicht in:Advanced science 2024-12, p.e2410107
Hauptverfasser: Ma, Chuchu, Jiang, Yuyu, Xiang, Yan, Li, Chang, Xie, Xiaoying, Zhang, Yunkai, You, Yang, Xie, Laozhi, Gong, Jianing, Sun, Yinzhe, Tong, Shiqiang, Song, Qingxiang, Chen, Jun, Xiao, Wenze
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Sprache:eng
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