SENP6-Mediated deSUMOylation of Nrf2 Exacerbates Neuronal Oxidative Stress Following Cerebral Ischemia and Reperfusion Injury

Oxidative stress is believed to play critical pathophysiological roles in ischemic brain injury, and the nuclear factor erythroid 2-related factor 2 (Nrf2) signaling pathway is recognized as the most crucial endogenous antioxidant stress damage route. Some research have demonstrated that Nrf2 play c...

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Veröffentlicht in:Advanced science 2024-12, p.e2410410
Hauptverfasser: Xia, Qian, Que, Mengxin, Zhan, Gaofeng, Zhang, Longqing, Zhang, Xue, Zhao, Yilin, Zhou, Huijuan, Zheng, Lu, Mao, Meng, Li, Xing
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Sprache:eng
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