DNA Mimic Foldamer Recognition of a Chromosomal Protein

Helical aromatic oligoamide foldamers bearing anionic side chains that mimic the overall shape and charge surface distribution of DNA were synthesized. Their interactions with chromosomal protein Sac7d, a non-sequence-selective DNA-binder that kinks DNA, were investigated by Surface Plasmon Resonanc...

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Veröffentlicht in:Angewandte Chemie International Edition 2024-12, p.e202422958
Hauptverfasser: Deepak, Deepak, Wu, Jiaojiao, Corvaglia, Valentina, Allmendinger, Lars, Scheckenbach, Michael, Tinnefeld, Philip, Huc, Ivan
Format: Artikel
Sprache:eng
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