The effects of microsurgical varicocelectomy performed for infertility on premature ejaculation
To investigate the effects of varicocelectomy on premature ejaculation (PE) in patients with varicocele and infertility. A total of 82 sexually active patients aged 18 years or over who had undergone microscopic subinguinal varicocelectomy with a clinical diagnosis of varicocele in 14 urology clinic...
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creator | Kizilkan, Yalcin Duran, Mesut Berkan Kayra, Mehmet Vehbi Sahin, Bahadir Toksoz, Serdar Gultekin, Mehmet Hamza Yildirim, Omer Gul, Murat Akdogan, Nebil Akbaba, Kagan Turker Ure, Iyimser Hasirci, Eray Kahraman, Oguzhan Ceyhan, Erman Yavuz, Abdulmecit Akgun, Ugur Cinar, Onder Gul, Umit Deliktas, Hasan Ozkara, Hamdi Turunc, Tahsin |
description | To investigate the effects of varicocelectomy on premature ejaculation (PE) in patients with varicocele and infertility.
A total of 82 sexually active patients aged 18 years or over who had undergone microscopic subinguinal varicocelectomy with a clinical diagnosis of varicocele in 14 urology clinics between October 2021 and March 2023 with primary infertility were evaluated prospectively Patients were evaluated using the Turkish validated form of the 'Premature Ejaculation Diagnostic Tool' (PEDT) scale. A PEDT score of 11 or above was taken to indicate the presence of PE. Turkish validated forms of PEDT and International Index of Erectile Function-5 (IIEF-5) were completed in all patients pre-operatively and at 3 and 6 months post-operatively. Intravaginal ejaculatory latency time (IELT) and serum testosterone measurements were also recorded.
Left varicocelectomy was performed in 70.7% and bilateral varicocelectomy in 29.3% of the participants. A significant difference was found between pre- and post-operative PEDT scores (× 2 (2) = 130.1, p |
doi_str_mv | 10.1007/s11255-024-04330-z |
format | Article |
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A total of 82 sexually active patients aged 18 years or over who had undergone microscopic subinguinal varicocelectomy with a clinical diagnosis of varicocele in 14 urology clinics between October 2021 and March 2023 with primary infertility were evaluated prospectively Patients were evaluated using the Turkish validated form of the 'Premature Ejaculation Diagnostic Tool' (PEDT) scale. A PEDT score of 11 or above was taken to indicate the presence of PE. Turkish validated forms of PEDT and International Index of Erectile Function-5 (IIEF-5) were completed in all patients pre-operatively and at 3 and 6 months post-operatively. Intravaginal ejaculatory latency time (IELT) and serum testosterone measurements were also recorded.
Left varicocelectomy was performed in 70.7% and bilateral varicocelectomy in 29.3% of the participants. A significant difference was found between pre- and post-operative PEDT scores (× 2 (2) = 130.1, p < 0.001). A significant difference was observed between pre- and post-operative IELT time (× 2 (2) = 143.2, p < 0.001). IIEF-5 scores differed before and after surgery (× 2 (2) = 59.5, p < 0.001). A difference was found between the testosterone levels measured before and after surgery (× 2 (2) = 40.9, p < 0.001). No statistically significant difference was observed between the third- and sixth-month testosterone values (p = 0.183). Testosterone levels (p = 0.001) and IELT scores (p < 0.001) were significantly higher, while PEDT scores (p < 0.001) were significantly lower in the bilateral varicocelectomy group at the sixth post-operative month.
In light of our findings, it is recommended that infertile patients with varicocele be informed of the positive effects of varicocelectomy on PE.]]></description><identifier>ISSN: 1573-2584</identifier><identifier>EISSN: 1573-2584</identifier><identifier>DOI: 10.1007/s11255-024-04330-z</identifier><identifier>PMID: 39708194</identifier><language>eng</language><publisher>Netherlands</publisher><ispartof>International urology and nephrology, 2024-12</ispartof><rights>2024. The Author(s), under exclusive licence to Springer Nature B.V.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c184t-8d7fa50119043951a6bc20f1ff84b9e5fe8f77881f465bb5ea47e7cd2466b7213</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/39708194$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kizilkan, Yalcin</creatorcontrib><creatorcontrib>Duran, Mesut Berkan</creatorcontrib><creatorcontrib>Kayra, Mehmet Vehbi</creatorcontrib><creatorcontrib>Sahin, Bahadir</creatorcontrib><creatorcontrib>Toksoz, Serdar</creatorcontrib><creatorcontrib>Gultekin, Mehmet Hamza</creatorcontrib><creatorcontrib>Yildirim, Omer</creatorcontrib><creatorcontrib>Gul, Murat</creatorcontrib><creatorcontrib>Akdogan, Nebil</creatorcontrib><creatorcontrib>Akbaba, Kagan Turker</creatorcontrib><creatorcontrib>Ure, Iyimser</creatorcontrib><creatorcontrib>Hasirci, Eray</creatorcontrib><creatorcontrib>Kahraman, Oguzhan</creatorcontrib><creatorcontrib>Ceyhan, Erman</creatorcontrib><creatorcontrib>Yavuz, Abdulmecit</creatorcontrib><creatorcontrib>Akgun, Ugur</creatorcontrib><creatorcontrib>Cinar, Onder</creatorcontrib><creatorcontrib>Gul, Umit</creatorcontrib><creatorcontrib>Deliktas, Hasan</creatorcontrib><creatorcontrib>Ozkara, Hamdi</creatorcontrib><creatorcontrib>Turunc, Tahsin</creatorcontrib><title>The effects of microsurgical varicocelectomy performed for infertility on premature ejaculation</title><title>International urology and nephrology</title><addtitle>Int Urol Nephrol</addtitle><description><![CDATA[To investigate the effects of varicocelectomy on premature ejaculation (PE) in patients with varicocele and infertility.
A total of 82 sexually active patients aged 18 years or over who had undergone microscopic subinguinal varicocelectomy with a clinical diagnosis of varicocele in 14 urology clinics between October 2021 and March 2023 with primary infertility were evaluated prospectively Patients were evaluated using the Turkish validated form of the 'Premature Ejaculation Diagnostic Tool' (PEDT) scale. A PEDT score of 11 or above was taken to indicate the presence of PE. Turkish validated forms of PEDT and International Index of Erectile Function-5 (IIEF-5) were completed in all patients pre-operatively and at 3 and 6 months post-operatively. Intravaginal ejaculatory latency time (IELT) and serum testosterone measurements were also recorded.
Left varicocelectomy was performed in 70.7% and bilateral varicocelectomy in 29.3% of the participants. A significant difference was found between pre- and post-operative PEDT scores (× 2 (2) = 130.1, p < 0.001). A significant difference was observed between pre- and post-operative IELT time (× 2 (2) = 143.2, p < 0.001). IIEF-5 scores differed before and after surgery (× 2 (2) = 59.5, p < 0.001). A difference was found between the testosterone levels measured before and after surgery (× 2 (2) = 40.9, p < 0.001). No statistically significant difference was observed between the third- and sixth-month testosterone values (p = 0.183). Testosterone levels (p = 0.001) and IELT scores (p < 0.001) were significantly higher, while PEDT scores (p < 0.001) were significantly lower in the bilateral varicocelectomy group at the sixth post-operative month.
In light of our findings, it is recommended that infertile patients with varicocele be informed of the positive effects of varicocelectomy on PE.]]></description><issn>1573-2584</issn><issn>1573-2584</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><recordid>eNpNkM1OwzAQhC0EoqXwAhyQj1wCdmLH9hFV_ElIXMrZctw1uEriYidI7dPj0oI47Uo7M9r5ELqk5IYSIm4TpSXnBSlZQVhVkWJ7hKaUi6oouWTH__YJOktpRQhRkpBTNKmUIJIqNkV68QEYnAM7JBwc7ryNIY3x3VvT4i8TvQ0W2nwO3QavIboQO1jiPLDvHcTBt37Y4NDjdYTODGPMeStjx9YMPvTn6MSZNsHFYc7Q28P9Yv5UvLw-Ps_vXgpLJRsKuRTOcEKpyk0Up6ZubEkcdU6yRgF3IJ0QUlLHat40HAwTIOyyZHXdiJJWM3S9z13H8DlCGnTnU368NT2EMemKMqEEl0pmabmX7pqmCE6vo-9M3GhK9A6s3oPVGaz-Aau32XR1yB-b3P_P8kuy-gaBjXX_</recordid><startdate>20241221</startdate><enddate>20241221</enddate><creator>Kizilkan, Yalcin</creator><creator>Duran, Mesut Berkan</creator><creator>Kayra, Mehmet Vehbi</creator><creator>Sahin, Bahadir</creator><creator>Toksoz, Serdar</creator><creator>Gultekin, Mehmet Hamza</creator><creator>Yildirim, Omer</creator><creator>Gul, Murat</creator><creator>Akdogan, Nebil</creator><creator>Akbaba, Kagan Turker</creator><creator>Ure, Iyimser</creator><creator>Hasirci, Eray</creator><creator>Kahraman, Oguzhan</creator><creator>Ceyhan, Erman</creator><creator>Yavuz, Abdulmecit</creator><creator>Akgun, Ugur</creator><creator>Cinar, Onder</creator><creator>Gul, Umit</creator><creator>Deliktas, Hasan</creator><creator>Ozkara, Hamdi</creator><creator>Turunc, Tahsin</creator><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20241221</creationdate><title>The effects of microsurgical varicocelectomy performed for infertility on premature ejaculation</title><author>Kizilkan, Yalcin ; Duran, Mesut Berkan ; Kayra, Mehmet Vehbi ; Sahin, Bahadir ; Toksoz, Serdar ; Gultekin, Mehmet Hamza ; Yildirim, Omer ; Gul, Murat ; Akdogan, Nebil ; Akbaba, Kagan Turker ; Ure, Iyimser ; Hasirci, Eray ; Kahraman, Oguzhan ; Ceyhan, Erman ; Yavuz, Abdulmecit ; Akgun, Ugur ; Cinar, Onder ; Gul, Umit ; Deliktas, Hasan ; Ozkara, Hamdi ; Turunc, Tahsin</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c184t-8d7fa50119043951a6bc20f1ff84b9e5fe8f77881f465bb5ea47e7cd2466b7213</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kizilkan, Yalcin</creatorcontrib><creatorcontrib>Duran, Mesut Berkan</creatorcontrib><creatorcontrib>Kayra, Mehmet Vehbi</creatorcontrib><creatorcontrib>Sahin, Bahadir</creatorcontrib><creatorcontrib>Toksoz, Serdar</creatorcontrib><creatorcontrib>Gultekin, Mehmet Hamza</creatorcontrib><creatorcontrib>Yildirim, Omer</creatorcontrib><creatorcontrib>Gul, Murat</creatorcontrib><creatorcontrib>Akdogan, Nebil</creatorcontrib><creatorcontrib>Akbaba, Kagan Turker</creatorcontrib><creatorcontrib>Ure, Iyimser</creatorcontrib><creatorcontrib>Hasirci, Eray</creatorcontrib><creatorcontrib>Kahraman, Oguzhan</creatorcontrib><creatorcontrib>Ceyhan, Erman</creatorcontrib><creatorcontrib>Yavuz, Abdulmecit</creatorcontrib><creatorcontrib>Akgun, Ugur</creatorcontrib><creatorcontrib>Cinar, Onder</creatorcontrib><creatorcontrib>Gul, Umit</creatorcontrib><creatorcontrib>Deliktas, Hasan</creatorcontrib><creatorcontrib>Ozkara, Hamdi</creatorcontrib><creatorcontrib>Turunc, Tahsin</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>International urology and nephrology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kizilkan, Yalcin</au><au>Duran, Mesut Berkan</au><au>Kayra, Mehmet Vehbi</au><au>Sahin, Bahadir</au><au>Toksoz, Serdar</au><au>Gultekin, Mehmet Hamza</au><au>Yildirim, Omer</au><au>Gul, Murat</au><au>Akdogan, Nebil</au><au>Akbaba, Kagan Turker</au><au>Ure, Iyimser</au><au>Hasirci, Eray</au><au>Kahraman, Oguzhan</au><au>Ceyhan, Erman</au><au>Yavuz, Abdulmecit</au><au>Akgun, Ugur</au><au>Cinar, Onder</au><au>Gul, Umit</au><au>Deliktas, Hasan</au><au>Ozkara, Hamdi</au><au>Turunc, Tahsin</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The effects of microsurgical varicocelectomy performed for infertility on premature ejaculation</atitle><jtitle>International urology and nephrology</jtitle><addtitle>Int Urol Nephrol</addtitle><date>2024-12-21</date><risdate>2024</risdate><issn>1573-2584</issn><eissn>1573-2584</eissn><abstract><![CDATA[To investigate the effects of varicocelectomy on premature ejaculation (PE) in patients with varicocele and infertility.
A total of 82 sexually active patients aged 18 years or over who had undergone microscopic subinguinal varicocelectomy with a clinical diagnosis of varicocele in 14 urology clinics between October 2021 and March 2023 with primary infertility were evaluated prospectively Patients were evaluated using the Turkish validated form of the 'Premature Ejaculation Diagnostic Tool' (PEDT) scale. A PEDT score of 11 or above was taken to indicate the presence of PE. Turkish validated forms of PEDT and International Index of Erectile Function-5 (IIEF-5) were completed in all patients pre-operatively and at 3 and 6 months post-operatively. Intravaginal ejaculatory latency time (IELT) and serum testosterone measurements were also recorded.
Left varicocelectomy was performed in 70.7% and bilateral varicocelectomy in 29.3% of the participants. A significant difference was found between pre- and post-operative PEDT scores (× 2 (2) = 130.1, p < 0.001). A significant difference was observed between pre- and post-operative IELT time (× 2 (2) = 143.2, p < 0.001). IIEF-5 scores differed before and after surgery (× 2 (2) = 59.5, p < 0.001). A difference was found between the testosterone levels measured before and after surgery (× 2 (2) = 40.9, p < 0.001). No statistically significant difference was observed between the third- and sixth-month testosterone values (p = 0.183). Testosterone levels (p = 0.001) and IELT scores (p < 0.001) were significantly higher, while PEDT scores (p < 0.001) were significantly lower in the bilateral varicocelectomy group at the sixth post-operative month.
In light of our findings, it is recommended that infertile patients with varicocele be informed of the positive effects of varicocelectomy on PE.]]></abstract><cop>Netherlands</cop><pmid>39708194</pmid><doi>10.1007/s11255-024-04330-z</doi></addata></record> |
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title | The effects of microsurgical varicocelectomy performed for infertility on premature ejaculation |
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