Hierarchical Targeting Nanodrug with Holistic DNA Protection for Effective Treatment of Acute Kidney Injury

Acute kidney injury (AKI) manifests a hallmark pathological feature of extensive and severe DNA damage in renal tubules, primarily induced by the excessive of toxic reactive oxygen species (ROS) from the mitochondrial electron transport chain. The kidney's complex intricate physiological archit...

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Veröffentlicht in:Advanced science 2024-12, p.e2411254
Hauptverfasser: Chen, Qiaohui, Yang, Yongqi, Ying, Xiaohong, Huang, Changkun, Chen, Jianlin, Wang, Jue, Wu, Ziyu, Zeng, Wan, Miao, Chenxi, Shi, Xiaojing, Nan, Yayun, Huang, Qiong, Ai, Kelong
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Sprache:eng
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