Characterization of Human CD8αβ Interaction With Classical and Unconventional MHC Molecules

The CD8 co-receptor exists as both an αα homodimer, expressed on subsets of specialized lymphoid cells, and as an αβ heterodimer, which is the canonical co-receptor on cytotoxic T-cells, tuning TCR thymic selection and antigen-reactivity in the periphery. However, the biophysical parameters governin...

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Veröffentlicht in:	European journal of immunology 2024-12, p.e202451230
Hauptverfasser:	de Wet, Ben, Simmons, Robert Alan, Suckling, Richard J, Szoke-Kovacs, Rita, Mansour, Salah, Lepore, Marco, Cole, David K, Jaworski, Jakub, Chapman, Alexandra L, Aleksic, Milos
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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