Thiol functionalized pH-responsive mucoadhesive hydrogel: Potential approach for site-specific delivery of 5 fluorouracil in colon cancer

The present study aims to develop a novel thiolated carboxymethyl cellulose (CMC-SH) by the addition of aldehyde groups via oxidation followed by reductive amination and then develop CMC-SH based pH-responsive hydrogel by free radical polymerization approach while assessing its mucoadhesive and perm...

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Veröffentlicht in:	International journal of biological macromolecules 2025-02, Vol.289, p.138887, Article 138887
Hauptverfasser:	Hanan, Hanasul, Pervaiz, Fahad, Ijaz, Muhammad, Arshad, Tahreem, Saeed, Komal, Ahmad, Rizwan, Bukhari, Arshia Noor, Ain, Qurat ul, Javaid, Syeda Munazza
Format:	Artikel
Sprache:	eng
Schlagworte:	Carboxymethyl cellulose pH-responsive hydrogel Thiolation
Online-Zugang:	Volltext
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