Prevalence of Mitral Annular Disjunction at Cardiac MRI: Results from a Multicenter Registry
Purpose To determine the prevalence of mitral annular disjunction (MAD) in patients undergoing cardiac MRI for various clinical indications and to assess the association of MAD with arrhythmia, mitral valve prolapse (MVP), and myocardial alteration. Materials and Methods This study analyzed data fro...
Gespeichert in:
| Veröffentlicht in: | Radiology. Cardiothoracic imaging 2024-12, Vol.6 (6), p.e230428 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | 6 |
| container_start_page | e230428 |
| container_title | Radiology. Cardiothoracic imaging |
| container_volume | 6 |
| creator | Palmisano, Anna Bruno, Elisa Aquaro, Giovanni Donato De Gori, Carmelo Barbieri, Simone Adami, Margherita Plataroti, Dario Rondi, Paolo di Meo, Nunzia Ravanelli, Marco Farina, Davide Rossi, Alice Pradella, Silvia Miele, Vittorio Marchitelli, Livia Cundari, Giulia Galea, Nicola Tore, Davide Gatti, Marco Faletti, Riccardo Palumbo, Pierpaolo Di Cesare, Ernesto D'Angelo, Tommaso Lanzafame, Ludovica R M Blandino, Alfredo Dell'Aversana, Serena Ponsiglione, Andrea Ascione, Raffaele Imbriaco, Massimo Porcu, Michele Cau, Riccardo Saba, Luca Ferrandino, Giovanni Liguori, Carlo Sambuceti, Virginia Seitun, Sara Siani, Agnese Carriero, Alessandro Cosenza, Michele Lovato, Luigi Vignale, Davide Faggioni, Lorenzo Neri, Emanuele Esposito, Antonio |
| description | Purpose To determine the prevalence of mitral annular disjunction (MAD) in patients undergoing cardiac MRI for various clinical indications and to assess the association of MAD with arrhythmia, mitral valve prolapse (MVP), and myocardial alteration. Materials and Methods This study analyzed data from a retrospective observational registry of consecutive patients undergoing cardiac MRI for different clinical indications. Cardiac MRI examinations were performed from January 2019 to June 2019 at 13 Italian hospitals. Images underwent double reading by expert cardiac radiologists from the enrolling center and the core laboratory to assess the presence of MAD. Presence and maximum length of MAD and its association to MVP pattern, functional and structural myocardial alteration, and arrhythmia were evaluated using nonparametric and parametric tests. Logistic regression models were used to identify predictors of arrhythmia. Results Cardiac MRI studies from 2611 consecutive patients (1730, 66% male; median age, 53 years; IQR, 39-65 years) were evaluated. Prevalence of MAD was 5.44% (142 of 2611). MAD was an incidental finding in 74.6% (106 of 142) of patients. Patients with MAD had a higher prevalence of arrhythmias compared with patients without MAD (40% [57 of 142] vs 18% [444 of 2469];
< .001). Patients with MAD and bileaflet MVP showed a longer MAD compared with patients with single-leaflet or absent MVP (median, 7 mm [IQR, 3-9.5 mm] vs 4 mm [IQR, 3-5 mm];
< .001), a higher prevalence of systolic curling (75% [21 of 28] vs 30.7% [35 of 114];
< .001), higher extracellular volume values (30% [IQR, 28%-32%] vs 27% [IQR, 25%-30%];
= .04), and a higher prevalence of arrhythmia (64.2% [18 of 28] vs 34.2% [39 of 114];
= .006). MAD length of at least 5 mm was an independent predictor of arrhythmia (odds ratio 3.96; 95% CI: 1.93, 8.15;
< .001). Conclusion MAD was a frequent incidental finding on cardiac MRI scans from a multicenter registry. MAD length of at least 5 mm and coexisting bileaflet MVP showed a higher risk of arrhythmia.
MR Imaging, Cardiac, Mitral Annular Disjunction
©RSNA, 2024. |
| doi_str_mv | 10.1148/ryct.230428 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_3147134859</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>3147134859</sourcerecordid><originalsourceid>FETCH-LOGICAL-p564-d94e514266059548fd9bb58acae144542b5871f0545a4dfb0e331f5e1d0a8cd53</originalsourceid><addsrcrecordid>eNpNkM1LAzEQxYMottSevEuOXrYmm2S78VbqV6FFKT0KSzaZlZRstiZZof-9K1bw9ObxfjMMD6FrSmaU8vIuHHWa5YzwvDxD47xgZVZQJs7_zSM0jXFPCMkp54LKSzRispByWBqj97cAX8qB14C7Bm9sCsrhhfe9UwE_2LjvvU6281glvFTBWKXxZru6x1uIvUsRN6FrscKbwVgNPkEYog8bUzheoYtGuQjTk07Q7ulxt3zJ1q_Pq-VinR1EwTMjOQjK86IgQgpeNkbWtSiVVvDzMM8HM6cNEVwobpqaAGO0EUANUaU2gk3Q7e_ZQ-g-e4ipam3U4Jzy0PWxYpTPKeOlkAN6c0L7ugVTHYJtVThWf4Wwb4oVYlI</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>3147134859</pqid></control><display><type>article</type><title>Prevalence of Mitral Annular Disjunction at Cardiac MRI: Results from a Multicenter Registry</title><source>MEDLINE</source><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><creator>Palmisano, Anna ; Bruno, Elisa ; Aquaro, Giovanni Donato ; De Gori, Carmelo ; Barbieri, Simone ; Adami, Margherita ; Plataroti, Dario ; Rondi, Paolo ; di Meo, Nunzia ; Ravanelli, Marco ; Farina, Davide ; Rossi, Alice ; Pradella, Silvia ; Miele, Vittorio ; Marchitelli, Livia ; Cundari, Giulia ; Galea, Nicola ; Tore, Davide ; Gatti, Marco ; Faletti, Riccardo ; Palumbo, Pierpaolo ; Di Cesare, Ernesto ; D'Angelo, Tommaso ; Lanzafame, Ludovica R M ; Blandino, Alfredo ; Dell'Aversana, Serena ; Ponsiglione, Andrea ; Ascione, Raffaele ; Imbriaco, Massimo ; Porcu, Michele ; Cau, Riccardo ; Saba, Luca ; Ferrandino, Giovanni ; Liguori, Carlo ; Sambuceti, Virginia ; Seitun, Sara ; Siani, Agnese ; Carriero, Alessandro ; Cosenza, Michele ; Lovato, Luigi ; Vignale, Davide ; Faggioni, Lorenzo ; Neri, Emanuele ; Esposito, Antonio</creator><creatorcontrib>Palmisano, Anna ; Bruno, Elisa ; Aquaro, Giovanni Donato ; De Gori, Carmelo ; Barbieri, Simone ; Adami, Margherita ; Plataroti, Dario ; Rondi, Paolo ; di Meo, Nunzia ; Ravanelli, Marco ; Farina, Davide ; Rossi, Alice ; Pradella, Silvia ; Miele, Vittorio ; Marchitelli, Livia ; Cundari, Giulia ; Galea, Nicola ; Tore, Davide ; Gatti, Marco ; Faletti, Riccardo ; Palumbo, Pierpaolo ; Di Cesare, Ernesto ; D'Angelo, Tommaso ; Lanzafame, Ludovica R M ; Blandino, Alfredo ; Dell'Aversana, Serena ; Ponsiglione, Andrea ; Ascione, Raffaele ; Imbriaco, Massimo ; Porcu, Michele ; Cau, Riccardo ; Saba, Luca ; Ferrandino, Giovanni ; Liguori, Carlo ; Sambuceti, Virginia ; Seitun, Sara ; Siani, Agnese ; Carriero, Alessandro ; Cosenza, Michele ; Lovato, Luigi ; Vignale, Davide ; Faggioni, Lorenzo ; Neri, Emanuele ; Esposito, Antonio</creatorcontrib><description>Purpose To determine the prevalence of mitral annular disjunction (MAD) in patients undergoing cardiac MRI for various clinical indications and to assess the association of MAD with arrhythmia, mitral valve prolapse (MVP), and myocardial alteration. Materials and Methods This study analyzed data from a retrospective observational registry of consecutive patients undergoing cardiac MRI for different clinical indications. Cardiac MRI examinations were performed from January 2019 to June 2019 at 13 Italian hospitals. Images underwent double reading by expert cardiac radiologists from the enrolling center and the core laboratory to assess the presence of MAD. Presence and maximum length of MAD and its association to MVP pattern, functional and structural myocardial alteration, and arrhythmia were evaluated using nonparametric and parametric tests. Logistic regression models were used to identify predictors of arrhythmia. Results Cardiac MRI studies from 2611 consecutive patients (1730, 66% male; median age, 53 years; IQR, 39-65 years) were evaluated. Prevalence of MAD was 5.44% (142 of 2611). MAD was an incidental finding in 74.6% (106 of 142) of patients. Patients with MAD had a higher prevalence of arrhythmias compared with patients without MAD (40% [57 of 142] vs 18% [444 of 2469];
< .001). Patients with MAD and bileaflet MVP showed a longer MAD compared with patients with single-leaflet or absent MVP (median, 7 mm [IQR, 3-9.5 mm] vs 4 mm [IQR, 3-5 mm];
< .001), a higher prevalence of systolic curling (75% [21 of 28] vs 30.7% [35 of 114];
< .001), higher extracellular volume values (30% [IQR, 28%-32%] vs 27% [IQR, 25%-30%];
= .04), and a higher prevalence of arrhythmia (64.2% [18 of 28] vs 34.2% [39 of 114];
= .006). MAD length of at least 5 mm was an independent predictor of arrhythmia (odds ratio 3.96; 95% CI: 1.93, 8.15;
< .001). Conclusion MAD was a frequent incidental finding on cardiac MRI scans from a multicenter registry. MAD length of at least 5 mm and coexisting bileaflet MVP showed a higher risk of arrhythmia.
MR Imaging, Cardiac, Mitral Annular Disjunction
©RSNA, 2024.</description><identifier>ISSN: 2638-6135</identifier><identifier>EISSN: 2638-6135</identifier><identifier>DOI: 10.1148/ryct.230428</identifier><identifier>PMID: 39699304</identifier><language>eng</language><publisher>United States</publisher><subject>Adult ; Aged ; Arrhythmias, Cardiac - diagnostic imaging ; Arrhythmias, Cardiac - epidemiology ; Female ; Humans ; Italy - epidemiology ; Magnetic Resonance Imaging ; Magnetic Resonance Imaging, Cine - methods ; Male ; Middle Aged ; Mitral Valve - diagnostic imaging ; Mitral Valve - pathology ; Mitral Valve Prolapse - diagnostic imaging ; Mitral Valve Prolapse - epidemiology ; Prevalence ; Registries ; Retrospective Studies</subject><ispartof>Radiology. Cardiothoracic imaging, 2024-12, Vol.6 (6), p.e230428</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><orcidid>0000-0003-4708-5120 ; 0000-0002-8185-8636 ; 0000-0002-6051-3698 ; 0000-0003-3266-5245 ; 0000-0001-5262-5430 ; 0000-0001-5262-4489 ; 0000-0003-1642-4521 ; 0000-0003-0004-6378 ; 0000-0003-4070-1277 ; 0000-0002-2692-7432 ; 0000-0002-1170-6266 ; 0000-0003-1514-0092 ; 0000-0002-7848-1567 ; 0000-0001-8168-5280 ; 0000-0001-5898-870X ; 0000-0002-8865-8637 ; 0000-0002-3984-031X ; 0000-0001-7481-7169 ; 0000-0001-7950-4559 ; 0000-0002-7910-1087 ; 0000-0002-3090-8541 ; 0009-0006-2085-7230 ; 0000-0002-0995-3081 ; 0000-0003-2177-186X ; 0000-0002-5087-5740 ; 0009-0008-2450-1500 ; 0000-0002-4368-5498 ; 0000-0003-3559-7946 ; 0000-0002-1564-2060 ; 0009-0008-0930-1068</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/39699304$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Palmisano, Anna</creatorcontrib><creatorcontrib>Bruno, Elisa</creatorcontrib><creatorcontrib>Aquaro, Giovanni Donato</creatorcontrib><creatorcontrib>De Gori, Carmelo</creatorcontrib><creatorcontrib>Barbieri, Simone</creatorcontrib><creatorcontrib>Adami, Margherita</creatorcontrib><creatorcontrib>Plataroti, Dario</creatorcontrib><creatorcontrib>Rondi, Paolo</creatorcontrib><creatorcontrib>di Meo, Nunzia</creatorcontrib><creatorcontrib>Ravanelli, Marco</creatorcontrib><creatorcontrib>Farina, Davide</creatorcontrib><creatorcontrib>Rossi, Alice</creatorcontrib><creatorcontrib>Pradella, Silvia</creatorcontrib><creatorcontrib>Miele, Vittorio</creatorcontrib><creatorcontrib>Marchitelli, Livia</creatorcontrib><creatorcontrib>Cundari, Giulia</creatorcontrib><creatorcontrib>Galea, Nicola</creatorcontrib><creatorcontrib>Tore, Davide</creatorcontrib><creatorcontrib>Gatti, Marco</creatorcontrib><creatorcontrib>Faletti, Riccardo</creatorcontrib><creatorcontrib>Palumbo, Pierpaolo</creatorcontrib><creatorcontrib>Di Cesare, Ernesto</creatorcontrib><creatorcontrib>D'Angelo, Tommaso</creatorcontrib><creatorcontrib>Lanzafame, Ludovica R M</creatorcontrib><creatorcontrib>Blandino, Alfredo</creatorcontrib><creatorcontrib>Dell'Aversana, Serena</creatorcontrib><creatorcontrib>Ponsiglione, Andrea</creatorcontrib><creatorcontrib>Ascione, Raffaele</creatorcontrib><creatorcontrib>Imbriaco, Massimo</creatorcontrib><creatorcontrib>Porcu, Michele</creatorcontrib><creatorcontrib>Cau, Riccardo</creatorcontrib><creatorcontrib>Saba, Luca</creatorcontrib><creatorcontrib>Ferrandino, Giovanni</creatorcontrib><creatorcontrib>Liguori, Carlo</creatorcontrib><creatorcontrib>Sambuceti, Virginia</creatorcontrib><creatorcontrib>Seitun, Sara</creatorcontrib><creatorcontrib>Siani, Agnese</creatorcontrib><creatorcontrib>Carriero, Alessandro</creatorcontrib><creatorcontrib>Cosenza, Michele</creatorcontrib><creatorcontrib>Lovato, Luigi</creatorcontrib><creatorcontrib>Vignale, Davide</creatorcontrib><creatorcontrib>Faggioni, Lorenzo</creatorcontrib><creatorcontrib>Neri, Emanuele</creatorcontrib><creatorcontrib>Esposito, Antonio</creatorcontrib><title>Prevalence of Mitral Annular Disjunction at Cardiac MRI: Results from a Multicenter Registry</title><title>Radiology. Cardiothoracic imaging</title><addtitle>Radiol Cardiothorac Imaging</addtitle><description>Purpose To determine the prevalence of mitral annular disjunction (MAD) in patients undergoing cardiac MRI for various clinical indications and to assess the association of MAD with arrhythmia, mitral valve prolapse (MVP), and myocardial alteration. Materials and Methods This study analyzed data from a retrospective observational registry of consecutive patients undergoing cardiac MRI for different clinical indications. Cardiac MRI examinations were performed from January 2019 to June 2019 at 13 Italian hospitals. Images underwent double reading by expert cardiac radiologists from the enrolling center and the core laboratory to assess the presence of MAD. Presence and maximum length of MAD and its association to MVP pattern, functional and structural myocardial alteration, and arrhythmia were evaluated using nonparametric and parametric tests. Logistic regression models were used to identify predictors of arrhythmia. Results Cardiac MRI studies from 2611 consecutive patients (1730, 66% male; median age, 53 years; IQR, 39-65 years) were evaluated. Prevalence of MAD was 5.44% (142 of 2611). MAD was an incidental finding in 74.6% (106 of 142) of patients. Patients with MAD had a higher prevalence of arrhythmias compared with patients without MAD (40% [57 of 142] vs 18% [444 of 2469];
< .001). Patients with MAD and bileaflet MVP showed a longer MAD compared with patients with single-leaflet or absent MVP (median, 7 mm [IQR, 3-9.5 mm] vs 4 mm [IQR, 3-5 mm];
< .001), a higher prevalence of systolic curling (75% [21 of 28] vs 30.7% [35 of 114];
< .001), higher extracellular volume values (30% [IQR, 28%-32%] vs 27% [IQR, 25%-30%];
= .04), and a higher prevalence of arrhythmia (64.2% [18 of 28] vs 34.2% [39 of 114];
= .006). MAD length of at least 5 mm was an independent predictor of arrhythmia (odds ratio 3.96; 95% CI: 1.93, 8.15;
< .001). Conclusion MAD was a frequent incidental finding on cardiac MRI scans from a multicenter registry. MAD length of at least 5 mm and coexisting bileaflet MVP showed a higher risk of arrhythmia.
MR Imaging, Cardiac, Mitral Annular Disjunction
©RSNA, 2024.</description><subject>Adult</subject><subject>Aged</subject><subject>Arrhythmias, Cardiac - diagnostic imaging</subject><subject>Arrhythmias, Cardiac - epidemiology</subject><subject>Female</subject><subject>Humans</subject><subject>Italy - epidemiology</subject><subject>Magnetic Resonance Imaging</subject><subject>Magnetic Resonance Imaging, Cine - methods</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Mitral Valve - diagnostic imaging</subject><subject>Mitral Valve - pathology</subject><subject>Mitral Valve Prolapse - diagnostic imaging</subject><subject>Mitral Valve Prolapse - epidemiology</subject><subject>Prevalence</subject><subject>Registries</subject><subject>Retrospective Studies</subject><issn>2638-6135</issn><issn>2638-6135</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpNkM1LAzEQxYMottSevEuOXrYmm2S78VbqV6FFKT0KSzaZlZRstiZZof-9K1bw9ObxfjMMD6FrSmaU8vIuHHWa5YzwvDxD47xgZVZQJs7_zSM0jXFPCMkp54LKSzRispByWBqj97cAX8qB14C7Bm9sCsrhhfe9UwE_2LjvvU6281glvFTBWKXxZru6x1uIvUsRN6FrscKbwVgNPkEYog8bUzheoYtGuQjTk07Q7ulxt3zJ1q_Pq-VinR1EwTMjOQjK86IgQgpeNkbWtSiVVvDzMM8HM6cNEVwobpqaAGO0EUANUaU2gk3Q7e_ZQ-g-e4ipam3U4Jzy0PWxYpTPKeOlkAN6c0L7ugVTHYJtVThWf4Wwb4oVYlI</recordid><startdate>202412</startdate><enddate>202412</enddate><creator>Palmisano, Anna</creator><creator>Bruno, Elisa</creator><creator>Aquaro, Giovanni Donato</creator><creator>De Gori, Carmelo</creator><creator>Barbieri, Simone</creator><creator>Adami, Margherita</creator><creator>Plataroti, Dario</creator><creator>Rondi, Paolo</creator><creator>di Meo, Nunzia</creator><creator>Ravanelli, Marco</creator><creator>Farina, Davide</creator><creator>Rossi, Alice</creator><creator>Pradella, Silvia</creator><creator>Miele, Vittorio</creator><creator>Marchitelli, Livia</creator><creator>Cundari, Giulia</creator><creator>Galea, Nicola</creator><creator>Tore, Davide</creator><creator>Gatti, Marco</creator><creator>Faletti, Riccardo</creator><creator>Palumbo, Pierpaolo</creator><creator>Di Cesare, Ernesto</creator><creator>D'Angelo, Tommaso</creator><creator>Lanzafame, Ludovica R M</creator><creator>Blandino, Alfredo</creator><creator>Dell'Aversana, Serena</creator><creator>Ponsiglione, Andrea</creator><creator>Ascione, Raffaele</creator><creator>Imbriaco, Massimo</creator><creator>Porcu, Michele</creator><creator>Cau, Riccardo</creator><creator>Saba, Luca</creator><creator>Ferrandino, Giovanni</creator><creator>Liguori, Carlo</creator><creator>Sambuceti, Virginia</creator><creator>Seitun, Sara</creator><creator>Siani, Agnese</creator><creator>Carriero, Alessandro</creator><creator>Cosenza, Michele</creator><creator>Lovato, Luigi</creator><creator>Vignale, Davide</creator><creator>Faggioni, Lorenzo</creator><creator>Neri, Emanuele</creator><creator>Esposito, Antonio</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-4708-5120</orcidid><orcidid>https://orcid.org/0000-0002-8185-8636</orcidid><orcidid>https://orcid.org/0000-0002-6051-3698</orcidid><orcidid>https://orcid.org/0000-0003-3266-5245</orcidid><orcidid>https://orcid.org/0000-0001-5262-5430</orcidid><orcidid>https://orcid.org/0000-0001-5262-4489</orcidid><orcidid>https://orcid.org/0000-0003-1642-4521</orcidid><orcidid>https://orcid.org/0000-0003-0004-6378</orcidid><orcidid>https://orcid.org/0000-0003-4070-1277</orcidid><orcidid>https://orcid.org/0000-0002-2692-7432</orcidid><orcidid>https://orcid.org/0000-0002-1170-6266</orcidid><orcidid>https://orcid.org/0000-0003-1514-0092</orcidid><orcidid>https://orcid.org/0000-0002-7848-1567</orcidid><orcidid>https://orcid.org/0000-0001-8168-5280</orcidid><orcidid>https://orcid.org/0000-0001-5898-870X</orcidid><orcidid>https://orcid.org/0000-0002-8865-8637</orcidid><orcidid>https://orcid.org/0000-0002-3984-031X</orcidid><orcidid>https://orcid.org/0000-0001-7481-7169</orcidid><orcidid>https://orcid.org/0000-0001-7950-4559</orcidid><orcidid>https://orcid.org/0000-0002-7910-1087</orcidid><orcidid>https://orcid.org/0000-0002-3090-8541</orcidid><orcidid>https://orcid.org/0009-0006-2085-7230</orcidid><orcidid>https://orcid.org/0000-0002-0995-3081</orcidid><orcidid>https://orcid.org/0000-0003-2177-186X</orcidid><orcidid>https://orcid.org/0000-0002-5087-5740</orcidid><orcidid>https://orcid.org/0009-0008-2450-1500</orcidid><orcidid>https://orcid.org/0000-0002-4368-5498</orcidid><orcidid>https://orcid.org/0000-0003-3559-7946</orcidid><orcidid>https://orcid.org/0000-0002-1564-2060</orcidid><orcidid>https://orcid.org/0009-0008-0930-1068</orcidid></search><sort><creationdate>202412</creationdate><title>Prevalence of Mitral Annular Disjunction at Cardiac MRI: Results from a Multicenter Registry</title><author>Palmisano, Anna ; Bruno, Elisa ; Aquaro, Giovanni Donato ; De Gori, Carmelo ; Barbieri, Simone ; Adami, Margherita ; Plataroti, Dario ; Rondi, Paolo ; di Meo, Nunzia ; Ravanelli, Marco ; Farina, Davide ; Rossi, Alice ; Pradella, Silvia ; Miele, Vittorio ; Marchitelli, Livia ; Cundari, Giulia ; Galea, Nicola ; Tore, Davide ; Gatti, Marco ; Faletti, Riccardo ; Palumbo, Pierpaolo ; Di Cesare, Ernesto ; D'Angelo, Tommaso ; Lanzafame, Ludovica R M ; Blandino, Alfredo ; Dell'Aversana, Serena ; Ponsiglione, Andrea ; Ascione, Raffaele ; Imbriaco, Massimo ; Porcu, Michele ; Cau, Riccardo ; Saba, Luca ; Ferrandino, Giovanni ; Liguori, Carlo ; Sambuceti, Virginia ; Seitun, Sara ; Siani, Agnese ; Carriero, Alessandro ; Cosenza, Michele ; Lovato, Luigi ; Vignale, Davide ; Faggioni, Lorenzo ; Neri, Emanuele ; Esposito, Antonio</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p564-d94e514266059548fd9bb58acae144542b5871f0545a4dfb0e331f5e1d0a8cd53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Arrhythmias, Cardiac - diagnostic imaging</topic><topic>Arrhythmias, Cardiac - epidemiology</topic><topic>Female</topic><topic>Humans</topic><topic>Italy - epidemiology</topic><topic>Magnetic Resonance Imaging</topic><topic>Magnetic Resonance Imaging, Cine - methods</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Mitral Valve - diagnostic imaging</topic><topic>Mitral Valve - pathology</topic><topic>Mitral Valve Prolapse - diagnostic imaging</topic><topic>Mitral Valve Prolapse - epidemiology</topic><topic>Prevalence</topic><topic>Registries</topic><topic>Retrospective Studies</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Palmisano, Anna</creatorcontrib><creatorcontrib>Bruno, Elisa</creatorcontrib><creatorcontrib>Aquaro, Giovanni Donato</creatorcontrib><creatorcontrib>De Gori, Carmelo</creatorcontrib><creatorcontrib>Barbieri, Simone</creatorcontrib><creatorcontrib>Adami, Margherita</creatorcontrib><creatorcontrib>Plataroti, Dario</creatorcontrib><creatorcontrib>Rondi, Paolo</creatorcontrib><creatorcontrib>di Meo, Nunzia</creatorcontrib><creatorcontrib>Ravanelli, Marco</creatorcontrib><creatorcontrib>Farina, Davide</creatorcontrib><creatorcontrib>Rossi, Alice</creatorcontrib><creatorcontrib>Pradella, Silvia</creatorcontrib><creatorcontrib>Miele, Vittorio</creatorcontrib><creatorcontrib>Marchitelli, Livia</creatorcontrib><creatorcontrib>Cundari, Giulia</creatorcontrib><creatorcontrib>Galea, Nicola</creatorcontrib><creatorcontrib>Tore, Davide</creatorcontrib><creatorcontrib>Gatti, Marco</creatorcontrib><creatorcontrib>Faletti, Riccardo</creatorcontrib><creatorcontrib>Palumbo, Pierpaolo</creatorcontrib><creatorcontrib>Di Cesare, Ernesto</creatorcontrib><creatorcontrib>D'Angelo, Tommaso</creatorcontrib><creatorcontrib>Lanzafame, Ludovica R M</creatorcontrib><creatorcontrib>Blandino, Alfredo</creatorcontrib><creatorcontrib>Dell'Aversana, Serena</creatorcontrib><creatorcontrib>Ponsiglione, Andrea</creatorcontrib><creatorcontrib>Ascione, Raffaele</creatorcontrib><creatorcontrib>Imbriaco, Massimo</creatorcontrib><creatorcontrib>Porcu, Michele</creatorcontrib><creatorcontrib>Cau, Riccardo</creatorcontrib><creatorcontrib>Saba, Luca</creatorcontrib><creatorcontrib>Ferrandino, Giovanni</creatorcontrib><creatorcontrib>Liguori, Carlo</creatorcontrib><creatorcontrib>Sambuceti, Virginia</creatorcontrib><creatorcontrib>Seitun, Sara</creatorcontrib><creatorcontrib>Siani, Agnese</creatorcontrib><creatorcontrib>Carriero, Alessandro</creatorcontrib><creatorcontrib>Cosenza, Michele</creatorcontrib><creatorcontrib>Lovato, Luigi</creatorcontrib><creatorcontrib>Vignale, Davide</creatorcontrib><creatorcontrib>Faggioni, Lorenzo</creatorcontrib><creatorcontrib>Neri, Emanuele</creatorcontrib><creatorcontrib>Esposito, Antonio</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Radiology. Cardiothoracic imaging</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Palmisano, Anna</au><au>Bruno, Elisa</au><au>Aquaro, Giovanni Donato</au><au>De Gori, Carmelo</au><au>Barbieri, Simone</au><au>Adami, Margherita</au><au>Plataroti, Dario</au><au>Rondi, Paolo</au><au>di Meo, Nunzia</au><au>Ravanelli, Marco</au><au>Farina, Davide</au><au>Rossi, Alice</au><au>Pradella, Silvia</au><au>Miele, Vittorio</au><au>Marchitelli, Livia</au><au>Cundari, Giulia</au><au>Galea, Nicola</au><au>Tore, Davide</au><au>Gatti, Marco</au><au>Faletti, Riccardo</au><au>Palumbo, Pierpaolo</au><au>Di Cesare, Ernesto</au><au>D'Angelo, Tommaso</au><au>Lanzafame, Ludovica R M</au><au>Blandino, Alfredo</au><au>Dell'Aversana, Serena</au><au>Ponsiglione, Andrea</au><au>Ascione, Raffaele</au><au>Imbriaco, Massimo</au><au>Porcu, Michele</au><au>Cau, Riccardo</au><au>Saba, Luca</au><au>Ferrandino, Giovanni</au><au>Liguori, Carlo</au><au>Sambuceti, Virginia</au><au>Seitun, Sara</au><au>Siani, Agnese</au><au>Carriero, Alessandro</au><au>Cosenza, Michele</au><au>Lovato, Luigi</au><au>Vignale, Davide</au><au>Faggioni, Lorenzo</au><au>Neri, Emanuele</au><au>Esposito, Antonio</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prevalence of Mitral Annular Disjunction at Cardiac MRI: Results from a Multicenter Registry</atitle><jtitle>Radiology. Cardiothoracic imaging</jtitle><addtitle>Radiol Cardiothorac Imaging</addtitle><date>2024-12</date><risdate>2024</risdate><volume>6</volume><issue>6</issue><spage>e230428</spage><pages>e230428-</pages><issn>2638-6135</issn><eissn>2638-6135</eissn><abstract>Purpose To determine the prevalence of mitral annular disjunction (MAD) in patients undergoing cardiac MRI for various clinical indications and to assess the association of MAD with arrhythmia, mitral valve prolapse (MVP), and myocardial alteration. Materials and Methods This study analyzed data from a retrospective observational registry of consecutive patients undergoing cardiac MRI for different clinical indications. Cardiac MRI examinations were performed from January 2019 to June 2019 at 13 Italian hospitals. Images underwent double reading by expert cardiac radiologists from the enrolling center and the core laboratory to assess the presence of MAD. Presence and maximum length of MAD and its association to MVP pattern, functional and structural myocardial alteration, and arrhythmia were evaluated using nonparametric and parametric tests. Logistic regression models were used to identify predictors of arrhythmia. Results Cardiac MRI studies from 2611 consecutive patients (1730, 66% male; median age, 53 years; IQR, 39-65 years) were evaluated. Prevalence of MAD was 5.44% (142 of 2611). MAD was an incidental finding in 74.6% (106 of 142) of patients. Patients with MAD had a higher prevalence of arrhythmias compared with patients without MAD (40% [57 of 142] vs 18% [444 of 2469];
< .001). Patients with MAD and bileaflet MVP showed a longer MAD compared with patients with single-leaflet or absent MVP (median, 7 mm [IQR, 3-9.5 mm] vs 4 mm [IQR, 3-5 mm];
< .001), a higher prevalence of systolic curling (75% [21 of 28] vs 30.7% [35 of 114];
< .001), higher extracellular volume values (30% [IQR, 28%-32%] vs 27% [IQR, 25%-30%];
= .04), and a higher prevalence of arrhythmia (64.2% [18 of 28] vs 34.2% [39 of 114];
= .006). MAD length of at least 5 mm was an independent predictor of arrhythmia (odds ratio 3.96; 95% CI: 1.93, 8.15;
< .001). Conclusion MAD was a frequent incidental finding on cardiac MRI scans from a multicenter registry. MAD length of at least 5 mm and coexisting bileaflet MVP showed a higher risk of arrhythmia.
MR Imaging, Cardiac, Mitral Annular Disjunction
©RSNA, 2024.</abstract><cop>United States</cop><pmid>39699304</pmid><doi>10.1148/ryct.230428</doi><orcidid>https://orcid.org/0000-0003-4708-5120</orcidid><orcidid>https://orcid.org/0000-0002-8185-8636</orcidid><orcidid>https://orcid.org/0000-0002-6051-3698</orcidid><orcidid>https://orcid.org/0000-0003-3266-5245</orcidid><orcidid>https://orcid.org/0000-0001-5262-5430</orcidid><orcidid>https://orcid.org/0000-0001-5262-4489</orcidid><orcidid>https://orcid.org/0000-0003-1642-4521</orcidid><orcidid>https://orcid.org/0000-0003-0004-6378</orcidid><orcidid>https://orcid.org/0000-0003-4070-1277</orcidid><orcidid>https://orcid.org/0000-0002-2692-7432</orcidid><orcidid>https://orcid.org/0000-0002-1170-6266</orcidid><orcidid>https://orcid.org/0000-0003-1514-0092</orcidid><orcidid>https://orcid.org/0000-0002-7848-1567</orcidid><orcidid>https://orcid.org/0000-0001-8168-5280</orcidid><orcidid>https://orcid.org/0000-0001-5898-870X</orcidid><orcidid>https://orcid.org/0000-0002-8865-8637</orcidid><orcidid>https://orcid.org/0000-0002-3984-031X</orcidid><orcidid>https://orcid.org/0000-0001-7481-7169</orcidid><orcidid>https://orcid.org/0000-0001-7950-4559</orcidid><orcidid>https://orcid.org/0000-0002-7910-1087</orcidid><orcidid>https://orcid.org/0000-0002-3090-8541</orcidid><orcidid>https://orcid.org/0009-0006-2085-7230</orcidid><orcidid>https://orcid.org/0000-0002-0995-3081</orcidid><orcidid>https://orcid.org/0000-0003-2177-186X</orcidid><orcidid>https://orcid.org/0000-0002-5087-5740</orcidid><orcidid>https://orcid.org/0009-0008-2450-1500</orcidid><orcidid>https://orcid.org/0000-0002-4368-5498</orcidid><orcidid>https://orcid.org/0000-0003-3559-7946</orcidid><orcidid>https://orcid.org/0000-0002-1564-2060</orcidid><orcidid>https://orcid.org/0009-0008-0930-1068</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 2638-6135 |
| ispartof | Radiology. Cardiothoracic imaging, 2024-12, Vol.6 (6), p.e230428 |
| issn | 2638-6135 2638-6135 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_3147134859 |
| source | MEDLINE; EZB-FREE-00999 freely available EZB journals; PubMed Central |
| subjects | Adult Aged Arrhythmias, Cardiac - diagnostic imaging Arrhythmias, Cardiac - epidemiology Female Humans Italy - epidemiology Magnetic Resonance Imaging Magnetic Resonance Imaging, Cine - methods Male Middle Aged Mitral Valve - diagnostic imaging Mitral Valve - pathology Mitral Valve Prolapse - diagnostic imaging Mitral Valve Prolapse - epidemiology Prevalence Registries Retrospective Studies |
| title | Prevalence of Mitral Annular Disjunction at Cardiac MRI: Results from a Multicenter Registry |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-02T20%3A24%3A31IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Prevalence%20of%20Mitral%20Annular%20Disjunction%20at%20Cardiac%20MRI:%20Results%20from%20a%20Multicenter%20Registry&rft.jtitle=Radiology.%20Cardiothoracic%20imaging&rft.au=Palmisano,%20Anna&rft.date=2024-12&rft.volume=6&rft.issue=6&rft.spage=e230428&rft.pages=e230428-&rft.issn=2638-6135&rft.eissn=2638-6135&rft_id=info:doi/10.1148/ryct.230428&rft_dat=%3Cproquest_pubme%3E3147134859%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=3147134859&rft_id=info:pmid/39699304&rfr_iscdi=true |