PRMT1-mediated methylation regulates MLL2 stability and gene expression

The interplay between multiple transcription factors precisely regulates eukaryotic transcription. Here, we report that the protein methyltransferases, MLL2/KMT2B and PRMT1, interact directly and act collectively to regulate gene expression. PRMT1 binds to the N-terminal region of MLL2, considered a...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Nucleic acids research 2024-12
Hauptverfasser:	An, Dongju, Kim, Jihyun, Moon, Byul, Kim, Hyoungmin, Nguyen, Hoa, Park, Sunghu, Lee, J Eugene, Kim, Jung-Ae, Kim, Jaehoon
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!