Atypical antipsychotic drug olanzapine inhibits 5-HT3 receptor-mediated currents by allosteric and non-competitive mechanisms

Olanzapine, an atypical antipsychotic, is widely used in the treatment of schizophrenia and bipolar disorder due to its modulation of dopamine and serotonin receptor systems. While its primary action involves antagonism of dopamine D2 and serotonin 5-HT (5-hydroxytryptamine)2A receptors, recent evid...

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Veröffentlicht in:	The Korean journal of physiology & pharmacology 2024-12
Hauptverfasser:	Park, Yong Soo, Kim, Gyu Min, Sung, Ho Jun, Yu, Ju Yeong, Sung, Ki-Wug
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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