Lonafarnib Protects Against Muscle Atrophy Induced by Dexamethasone

Muscle atrophy, including glucocorticoid-induced muscle wasting from treatments such as dexamethasone (DEX), results in significant reductions in muscle mass, strength and function. This study investigates the potential of lonafarnib, a farnesyltransferase inhibitor, to counteract DEX-induced muscle...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of cachexia, sarcopenia and muscle sarcopenia and muscle, 2025-02, Vol.16 (1), p.e13665
Hauptverfasser:	Bae, Sanghoon, Mai, Van-Hieu, Mun, Seyoung, Dong, Dalong, Han, Kyudong, Park, Sunghyouk, Hyun, Jung Keun
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Caenorhabditis elegans Cell Line Dexamethasone - pharmacology Dexamethasone - therapeutic use Dibenzocycloheptenes Disease Models, Animal Male Mice Muscle Fibers, Skeletal - drug effects Muscular Atrophy - chemically induced Piperidines - pharmacology Piperidines - therapeutic use Pyridines - pharmacology Pyridines - therapeutic use Rats Signal Transduction - drug effects
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!