Anti-Inflammatory Effects of Extracellular Vesicles from Ecklonia cava on 12-O-Tetradecanoylphorbol-13-Acetate-Induced Skin Inflammation in Mice

Steroids, which are often used to treat the inflammation associated with various skin diseases, have several negative side effects. As extract has anti-inflammatory effects in various diseases, we evaluated the efficacy of -derived extracellular vesicles (EVEs) in decreasing 12-O-tetradecanoylphorbo...

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Veröffentlicht in:	International journal of molecular sciences 2024-12, Vol.25 (23), p.12522
Hauptverfasser:	Kim, Geebum, Lee, So Young, Oh, Seyeon, Jang, Jong-Won, Lee, Jehyuk, Kim, Hyun-Seok, Son, Kuk Hui, Byun, Kyunghee
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetates Animal skins Animals Anti-Inflammatory Agents - pharmacology Anti-inflammatory drugs Apoptosis Cell death Chromosomal proteins Complications and side effects Dermatitis Dermatitis - drug therapy Dermatitis - etiology Dermatitis - metabolism Dermatitis - pathology Dermatologic agents Dermatology Extracellular vesicles Extracellular Vesicles - drug effects Extracellular Vesicles - metabolism Formulae, receipts, prescriptions Humans Inflammasomes - drug effects Inflammasomes - metabolism Inflammation Inflammation - chemically induced Inflammation - drug therapy Inflammation - metabolism Inflammation - pathology Inflammatory diseases Keratinocytes - drug effects Keratinocytes - metabolism Kinases Mice NF-kappa B - metabolism NLR Family, Pyrin Domain-Containing 3 Protein - metabolism Oxidative stress Pathogens Phaeophyceae - chemistry Proteins Psoriasis Skin Skin - drug effects Skin - metabolism Skin - pathology Skin diseases Tetradecanoylphorbol Acetate - adverse effects Tetradecanoylphorbol Acetate - toxicity Toll-Like Receptor 4 - metabolism Tumor necrosis factor-TNF
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