Evaluating the Safety of Immune Checkpoint Inhibitors and Combination Therapies in the Management of Brain Metastases: A Comprehensive Review

Brain metastases (BM) are a frequent and severe complication in patients with lung cancer, breast cancer, and melanoma. Immune checkpoint inhibitors (ICIs) have become a crucial treatment option for BM, whether used alone or in combination with chemotherapy and stereotactic radiosurgery (SRS). Howev...

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Veröffentlicht in:	Cancers 2024-12, Vol.16 (23), p.3929
Hauptverfasser:	Podder, Vivek, Ranjan, Tulika, Margolin, Kim, Maharaj, Arun, Ahluwalia, Manmeet Singh
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Asymptomatic Brain cancer Cancer therapies Chemotherapy Chronic illnesses Combination therapy Cytokines Cytotoxicity Drug therapy Drug therapy, Combination Hyperthyroidism Hypothyroidism Immune checkpoint inhibitors Inflammatory bowel disease Lung cancer Lung diseases Melanoma Metastases Metastasis Microbiota Neurotoxicity Pathophysiology Patient outcomes Radiation Radiosurgery Skin Steroids Thyroid gland
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