Antibody-Vincristine Conjugates as Potent Anticancer Therapeutic Agents

Antibody-drug conjugates (ADCs) are a well-established class of therapeutics primarily used in oncology to selectively deliver highly cytotoxic agents into cancer cells. While ADCs should theoretically spare healthy tissues and diminish side effects in patients, off-target toxicity is still observed...

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Veröffentlicht in:	Journal of medicinal chemistry 2024-12
Hauptverfasser:	Boos, Agathe, Most, Julien, Cahuzac, Héloïse, Moreira da Silva, Louis, Daubeuf, François, Erb, Stéphane, Cianférani, Sarah, Hernandez-Alba, Oscar, Semenchenko, Constantin, Dovgan, Igor, Kolodych, Sergii, Detappe, Alexandre, Dantzer, Françoise, Wagner, Alain, Zeniou, Maria, Chaubet, Guilhem
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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