Impact of smoking on gut microbiota and short-chain fatty acids in human and mice: Implications for COPD

•Cigarette smoke exposure reduces short-chain FA levels by altering gut microbiota.•A high-fiber diet counteract smoking-induced gut microbiota changes.•Diet-induced gut microbiota change mitigate lung inflammation and emphysema in COPD.•Targeting gut microbiota may alleviate COPD symptoms alongside...

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Veröffentlicht in:	Mucosal immunology 2024-12
Hauptverfasser:	Otake, Shiro, Chubachi, Shotaro, Miyamoto, Junki, Haneishi, Yuri, Arai, Tetsuya, Iizuka, Hideto, Shimada, Takashi, Sakurai, Kaori, Okuzumi, Shinichi, Kabata, Hiroki, Asakura, Takanori, Miyata, Jun, Irie, Junichiro, Asano, Koichiro, Nakamura, Hidetoshi, Kimura, Ikuo, Fukunaga, Koichi
Format:	Artikel
Sprache:	eng
Schlagworte:	Chronic obstructive pulmonary disease Gut-lung axis Microbiota
Online-Zugang:	Volltext
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