Dexamethasone Upregulates the Expression of the Human SLC26A3 (DRA, Down-Regulated in Adenoma) Transporter (an IBD Susceptibility Gene) in Intestinal Epithelial Cells and Attenuates Gut Inflammation

Down-Regulated in Adenoma (DRA) plays a critical role in intestinal chloride absorption and a decrease in its expression is a key event in diarrheal disorders. Recently, DRA has emerged as an Inflammatory Bowel Disease (IBD) susceptibility gene. Therefore, the strategies to upregulate DRA expression...

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Veröffentlicht in:Inflammatory bowel diseases 2024-12
Hauptverfasser: Kumar, Anoop, Husain, Nazim, Anbazhagan, Arivarasu N, Jayawardena, Dulari, Priyamvada, Shubha, Singhal, Megha, Jain, Charu, Kaur, Prabhdeep, Guzman, Grace, Saksena, Seema, Dudeja, Pradeep K
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Sprache:eng
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