Construction of cynomolgus monkey type 2 diabetes models by combining genetic prediction model with high-energy diet

Type 2 diabetes mellitus (T2D) is a significant health concern. Research using non-human primates, which develop T2D with similar symptoms and pancreatic changes as humans, is crucial but limited by long timelines and low success rates. We targeted capture sequenced 61 normal and 81 T2D cynomolgus m...

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Veröffentlicht in:	Biochimica et biophysica acta. Molecular basis of disease 2025-03, Vol.1871 (3), p.167616, Article 167616
Hauptverfasser:	Li, Ping, Ye, Huahu, Guo, Feng, Zheng, Jianhua, Shen, Wenlong, Xie, Dejian, Shi, Shu, Zhang, Yan, Fa, Yunzhi, Zhao, Zhihu
Format:	Artikel
Sprache:	eng
Schlagworte:	Genetic prediction model Machine learning Non-human primate Type 2 diabetes
Online-Zugang:	Volltext
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