Characterization and Inhibition of the Chaperone Function of Plasmodium falciparum Glucose-Regulated Protein 94 kDa (PfGrp94)

Plasmodium falciparum expresses four heat shock protein 90 (Hsp90) members. Among these, one, glucose-regulated protein 94 (PfGrp94), is localized in the endoplasmic reticulum (ER). Both the cytosolic and ER-based Hsp90s are essential for parasite survival under all growth conditions. The cytosolic...

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Veröffentlicht in:	Proteins, structure, function, and bioinformatics structure, function, and bioinformatics, 2024-12
Hauptverfasser:	Muzenda, Florence Lisa, Stofberg, Melissa Louise, Mthembu, Wendy, Achilonu, Ikechukwu, Strauss, Erick, Zininga, Tawanda
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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