Exploring habenular structural connectivity in Parkinson's disease: insights from 7 T MRI study

Background PD is marked by both motor and non-motor symptoms, with its pathophysiology involving many neural pathways and brain regions beyond the dopaminergic system. While mainly gray matter changes have been noted, white matter changes also exist in PD. Habenula, known for its role in reward proc...

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Veröffentlicht in:	Journal of neurology 2025, Vol.272 (1), p.8
Hauptverfasser:	Samanci, Bedia, Bayram, Ali, Tan, Sonny, Wanders, Meriek, Michielse, Stijn, Kuijf, Mark L., Temel, Yasin
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Cognition Dopamine receptors Female Globus pallidus Habenula Habenula - diagnostic imaging Habenula - physiopathology Humans Magnetic Resonance Imaging Male Medicine Medicine & Public Health Middle Aged Mood Movement disorders Neural networks Neural Pathways - diagnostic imaging Neural Pathways - physiopathology Neurodegenerative diseases Neurology Neuroradiology Neurosciences Nucleus accumbens Original Communication Parkinson Disease - diagnostic imaging Parkinson Disease - pathology Parkinson Disease - physiopathology Parkinson's disease Pathophysiology Patients Substantia alba Substantia grisea Therapeutic targets
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