Inter-center variations in inpatient outcomes for infants with gastroschisis from the Children's Hospitals Neonatal Consortium
To estimate inter-center variation (ICV) in hospital length of stay (LOS) and oral feeding at discharge among infants with gastroschisis. The Children's Hospitals Neonatal Consortium's (CHNC) database was used to identify hospitalized survivors with gastroschisis. Two outcomes were evaluat...
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creator | Ling, Con Yee Zaniletti, Isabella Riddle, Stefanie Elizabeth, Jacobson Korff, Stephanie G Chandler, Angela L Downey, L Corbin Padula, Michael A Evans, Jacquelyn R Grover, Theresa R Murthy, Karna |
description | To estimate inter-center variation (ICV) in hospital length of stay (LOS) and oral feeding at discharge among infants with gastroschisis.
The Children's Hospitals Neonatal Consortium's (CHNC) database was used to identify hospitalized survivors with gastroschisis. Two outcomes were evaluated: LOS and discharge without tube feedings. Hospital outcomes were evaluated in unadjusted and adjusted analyses. Generalized linear models with log link for gamma distribution were used to model LOS and logistic regression for discharge without tube feeds.
For 3987 surviving infants with gastroschisis, LOS and discharge within 70 days with exclusively oral feeding both exhibited significant ICV. Differences persisted in multivariable analyses. Risk-adjusted LOS (68% difference) and oral feeding at discharge (6.4-fold difference) varied significantly between centers.
Hospital of care was independently associated with LOS and exclusive oral feeding at discharge rates for infants with gastroschisis. Management differences, potentially influenced by parental preferences, contributed to variation. |
doi_str_mv | 10.1038/s41372-024-02160-6 |
format | Article |
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The Children's Hospitals Neonatal Consortium's (CHNC) database was used to identify hospitalized survivors with gastroschisis. Two outcomes were evaluated: LOS and discharge without tube feedings. Hospital outcomes were evaluated in unadjusted and adjusted analyses. Generalized linear models with log link for gamma distribution were used to model LOS and logistic regression for discharge without tube feeds.
For 3987 surviving infants with gastroschisis, LOS and discharge within 70 days with exclusively oral feeding both exhibited significant ICV. Differences persisted in multivariable analyses. Risk-adjusted LOS (68% difference) and oral feeding at discharge (6.4-fold difference) varied significantly between centers.
Hospital of care was independently associated with LOS and exclusive oral feeding at discharge rates for infants with gastroschisis. Management differences, potentially influenced by parental preferences, contributed to variation.</description><identifier>ISSN: 0743-8346</identifier><identifier>ISSN: 1476-5543</identifier><identifier>EISSN: 1476-5543</identifier><identifier>DOI: 10.1038/s41372-024-02160-6</identifier><identifier>PMID: 39663394</identifier><language>eng</language><publisher>United States</publisher><ispartof>Journal of perinatology, 2024-12</ispartof><rights>2024. The Author(s), under exclusive licence to Springer Nature America, Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c184t-2f1beb576f96866468cdb1fb2f6f87e3963b58886b68c01184a9bae574911cdb3</cites><orcidid>0000-0001-9945-6689 ; 0009-0004-2895-2393 ; 0009-0006-4288-2584 ; 0000-0003-1234-3468</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/39663394$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ling, Con Yee</creatorcontrib><creatorcontrib>Zaniletti, Isabella</creatorcontrib><creatorcontrib>Riddle, Stefanie</creatorcontrib><creatorcontrib>Elizabeth, Jacobson</creatorcontrib><creatorcontrib>Korff, Stephanie G</creatorcontrib><creatorcontrib>Chandler, Angela L</creatorcontrib><creatorcontrib>Downey, L Corbin</creatorcontrib><creatorcontrib>Padula, Michael A</creatorcontrib><creatorcontrib>Evans, Jacquelyn R</creatorcontrib><creatorcontrib>Grover, Theresa R</creatorcontrib><creatorcontrib>Murthy, Karna</creatorcontrib><creatorcontrib>Children’s Hospitals Neonatal Consortium Gastroschisis Focus Group</creatorcontrib><creatorcontrib>On behalf of Children’s Hospitals Neonatal Consortium Gastroschisis Focus Group</creatorcontrib><title>Inter-center variations in inpatient outcomes for infants with gastroschisis from the Children's Hospitals Neonatal Consortium</title><title>Journal of perinatology</title><addtitle>J Perinatol</addtitle><description>To estimate inter-center variation (ICV) in hospital length of stay (LOS) and oral feeding at discharge among infants with gastroschisis.
The Children's Hospitals Neonatal Consortium's (CHNC) database was used to identify hospitalized survivors with gastroschisis. Two outcomes were evaluated: LOS and discharge without tube feedings. Hospital outcomes were evaluated in unadjusted and adjusted analyses. Generalized linear models with log link for gamma distribution were used to model LOS and logistic regression for discharge without tube feeds.
For 3987 surviving infants with gastroschisis, LOS and discharge within 70 days with exclusively oral feeding both exhibited significant ICV. Differences persisted in multivariable analyses. Risk-adjusted LOS (68% difference) and oral feeding at discharge (6.4-fold difference) varied significantly between centers.
Hospital of care was independently associated with LOS and exclusive oral feeding at discharge rates for infants with gastroschisis. Management differences, potentially influenced by parental preferences, contributed to variation.</description><issn>0743-8346</issn><issn>1476-5543</issn><issn>1476-5543</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><recordid>eNo9kMFPwyAUxonRuDn9BzwYbnqpQqGUHk2jbsmiFz0T2oHFrGUC1Xjxb_fNTRPIA37f98j7EDqn5JoSJm8ip6zMM5Jz2FSQTBygKeWlyIqCs0M0JSVnmWRcTNBJjG-EbGF5jCasEoKxik_R92JIJmSt2Rb8oYPTyfkhYjfA2sAFCPZjan1vIrY-wLPVQ4r406UOv-qYgo9t56IDHHyPU2dw3bn1KpjhMuK5jxuX9DriR-MHDSdcwwc-JDf2p-jIAjJn-zpDL_d3z_U8Wz49LOrbZdZSyVOWW9qYpiiFrYQUggvZrhpqm9wKK0sD47CmkFKKBgih4NFVo01R8opSkLIZutr13QT_PpqYVO9ia9ZrPRg_RsUoF6KgVV6CNN9JW5grBmPVJrhehy9Fidrmrna5K8hd_eauBJgu9v3Hpjerf8tf0OwHbmSA7Q</recordid><startdate>20241211</startdate><enddate>20241211</enddate><creator>Ling, Con Yee</creator><creator>Zaniletti, Isabella</creator><creator>Riddle, Stefanie</creator><creator>Elizabeth, Jacobson</creator><creator>Korff, Stephanie G</creator><creator>Chandler, Angela L</creator><creator>Downey, L Corbin</creator><creator>Padula, Michael A</creator><creator>Evans, Jacquelyn R</creator><creator>Grover, Theresa R</creator><creator>Murthy, Karna</creator><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0001-9945-6689</orcidid><orcidid>https://orcid.org/0009-0004-2895-2393</orcidid><orcidid>https://orcid.org/0009-0006-4288-2584</orcidid><orcidid>https://orcid.org/0000-0003-1234-3468</orcidid></search><sort><creationdate>20241211</creationdate><title>Inter-center variations in inpatient outcomes for infants with gastroschisis from the Children's Hospitals Neonatal Consortium</title><author>Ling, Con Yee ; Zaniletti, Isabella ; Riddle, Stefanie ; Elizabeth, Jacobson ; Korff, Stephanie G ; Chandler, Angela L ; Downey, L Corbin ; Padula, Michael A ; Evans, Jacquelyn R ; Grover, Theresa R ; Murthy, Karna</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c184t-2f1beb576f96866468cdb1fb2f6f87e3963b58886b68c01184a9bae574911cdb3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ling, Con Yee</creatorcontrib><creatorcontrib>Zaniletti, Isabella</creatorcontrib><creatorcontrib>Riddle, Stefanie</creatorcontrib><creatorcontrib>Elizabeth, Jacobson</creatorcontrib><creatorcontrib>Korff, Stephanie G</creatorcontrib><creatorcontrib>Chandler, Angela L</creatorcontrib><creatorcontrib>Downey, L Corbin</creatorcontrib><creatorcontrib>Padula, Michael A</creatorcontrib><creatorcontrib>Evans, Jacquelyn R</creatorcontrib><creatorcontrib>Grover, Theresa R</creatorcontrib><creatorcontrib>Murthy, Karna</creatorcontrib><creatorcontrib>Children’s Hospitals Neonatal Consortium Gastroschisis Focus Group</creatorcontrib><creatorcontrib>On behalf of Children’s Hospitals Neonatal Consortium Gastroschisis Focus Group</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of perinatology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ling, Con Yee</au><au>Zaniletti, Isabella</au><au>Riddle, Stefanie</au><au>Elizabeth, Jacobson</au><au>Korff, Stephanie G</au><au>Chandler, Angela L</au><au>Downey, L Corbin</au><au>Padula, Michael A</au><au>Evans, Jacquelyn R</au><au>Grover, Theresa R</au><au>Murthy, Karna</au><aucorp>Children’s Hospitals Neonatal Consortium Gastroschisis Focus Group</aucorp><aucorp>On behalf of Children’s Hospitals Neonatal Consortium Gastroschisis Focus Group</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Inter-center variations in inpatient outcomes for infants with gastroschisis from the Children's Hospitals Neonatal Consortium</atitle><jtitle>Journal of perinatology</jtitle><addtitle>J Perinatol</addtitle><date>2024-12-11</date><risdate>2024</risdate><issn>0743-8346</issn><issn>1476-5543</issn><eissn>1476-5543</eissn><abstract>To estimate inter-center variation (ICV) in hospital length of stay (LOS) and oral feeding at discharge among infants with gastroschisis.
The Children's Hospitals Neonatal Consortium's (CHNC) database was used to identify hospitalized survivors with gastroschisis. Two outcomes were evaluated: LOS and discharge without tube feedings. Hospital outcomes were evaluated in unadjusted and adjusted analyses. Generalized linear models with log link for gamma distribution were used to model LOS and logistic regression for discharge without tube feeds.
For 3987 surviving infants with gastroschisis, LOS and discharge within 70 days with exclusively oral feeding both exhibited significant ICV. Differences persisted in multivariable analyses. Risk-adjusted LOS (68% difference) and oral feeding at discharge (6.4-fold difference) varied significantly between centers.
Hospital of care was independently associated with LOS and exclusive oral feeding at discharge rates for infants with gastroschisis. Management differences, potentially influenced by parental preferences, contributed to variation.</abstract><cop>United States</cop><pmid>39663394</pmid><doi>10.1038/s41372-024-02160-6</doi><orcidid>https://orcid.org/0000-0001-9945-6689</orcidid><orcidid>https://orcid.org/0009-0004-2895-2393</orcidid><orcidid>https://orcid.org/0009-0006-4288-2584</orcidid><orcidid>https://orcid.org/0000-0003-1234-3468</orcidid></addata></record> |
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title | Inter-center variations in inpatient outcomes for infants with gastroschisis from the Children's Hospitals Neonatal Consortium |
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