Modeling Clinical Radioiodine Uptake By Using Organoids Derived From Differentiated Thyroid Cancer

Radioiodine-refractory differentiated thyroid cancer (RAI-R DTC) accounts for the vast majority of thyroid-related mortality and, until recently, there were limited preclinical models for iodine uptake prediction. In the current study, we aim to establish a primary tumor-derived organoid model of DT...

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Veröffentlicht in:	Endocrinology (Philadelphia) 2024-11, Vol.166 (1)
Hauptverfasser:	Zhang, Xinyue, Liu, Jiaye, Ni, Yinyun, Yang, Ying, Tian, Tian, Zheng, Xiaofeng, Li, Zhihui, Huang, Rui
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Exome Sequencing Female Humans Iodine Radioisotopes Male Middle Aged Organoids - metabolism Thyroid Neoplasms - genetics Thyroid Neoplasms - metabolism Thyroid Neoplasms - pathology
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