Inositol 1,4,5-Trisphosphate Receptor 1 Gain-of-Function Increases the Risk for Cardiac Arrhythmias in Mice and Humans

Ca mishandling in cardiac Purkinje cells is a well-known cause of cardiac arrhythmias. The Purkinje cell resident inositol 1,4,5-trisphosphate receptor 1 (ITPR1) is believed to play an important role in Ca handling, and ITPR1 gain-of-function (GOF) has been implicated in cardiac arrhythmias. However...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Circulation (New York, N.Y.) N.Y.), 2024-12
Hauptverfasser:	Sun, Bo, Ni, Mingke, Li, Yanhui, Song, Zhenpeng, Wang, Hui, Zhu, Hai-Lei, Wei, Jinhong, Belke, Darrell, Cai, Shitian, Guo, Wenting, Yao, Jinjing, Tian, Shanshan, Estillore, John Paul, Wang, Ruiwu, Sondergaard, Mads Toft, Brohus, Malene, Rohde, Palle Duun, Mu, Yongxin, Vallmitjana, Alexander, Benitez, Raul, Hove-Madsen, Leif, Overgaard, Michael Toft, Fishman, Glenn I, Chen, Ju, Sanatani, Shubhayan, Wilde, Arthur A M, Fill, Michael, Ramos-Franco, Josefina, Nyegaard, Mette, Chen, S R Wayne
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!