Update to RIFM fragrance ingredient safety assessment, 4′-tert-butyl-2′,6′-dimethylacetophenone, CAS Registry Number 2040-10-0

•4′-tert-Butyl-2′,6′-dimethylacetophenone; a safety assessment based on RIFM's criteria.•A safety assessment based on 7 human health endpoints plus environmental.•All endpoints were cleared using target data, read-across, and/or TTC.

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Veröffentlicht in:Food and chemical toxicology 2024-12, Vol.197, p.115170, Article 115170
Hauptverfasser: Api, A.M., Bartlett, A., Belsito, D., Botelho, D., Bruze, M., Bryant-Friedrich, A., Burton, G.A., Cancellieri, M.A., Chon, H., Cronin, M., Crotty, S., Dagli, M.L., Dekant, W., Deodhar, C., Farrell, K., Fryer, A.D., Jones, L., Joshi, K., Lapczynski, A., Laskin, D.L., Lavelle, M., Lee, I., Moustakas, H., Muldoon, J., Penning, T.M., Piersma, A.H., Ritacco, G., Sadekar, N., Schember, I., Schultz, T.W., Siddiqi, F., Sipes, I.G., Sullivan, G., Thakkar, Y.
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container_issue
container_start_page 115170
container_title Food and chemical toxicology
container_volume 197
creator Api, A.M.
Bartlett, A.
Belsito, D.
Botelho, D.
Bruze, M.
Bryant-Friedrich, A.
Burton, G.A.
Cancellieri, M.A.
Chon, H.
Cronin, M.
Crotty, S.
Dagli, M.L.
Dekant, W.
Deodhar, C.
Farrell, K.
Fryer, A.D.
Jones, L.
Joshi, K.
Lapczynski, A.
Laskin, D.L.
Lavelle, M.
Lee, I.
Moustakas, H.
Muldoon, J.
Penning, T.M.
Piersma, A.H.
Ritacco, G.
Sadekar, N.
Schember, I.
Schultz, T.W.
Siddiqi, F.
Sipes, I.G.
Sullivan, G.
Thakkar, Y.
description •4′-tert-Butyl-2′,6′-dimethylacetophenone; a safety assessment based on RIFM's criteria.•A safety assessment based on 7 human health endpoints plus environmental.•All endpoints were cleared using target data, read-across, and/or TTC.
doi_str_mv 10.1016/j.fct.2024.115170
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title Update to RIFM fragrance ingredient safety assessment, 4′-tert-butyl-2′,6′-dimethylacetophenone, CAS Registry Number 2040-10-0
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