Progress Toward an Ideal Sleeping Pill

Thirty percent of Americans report insomnia. After eliminating obvious causes, the best therapy for insomnia is cognitive behavioral therapy, but this is not widely available. However, all the known oral sleeping aides are generally unsatisfactory. Recently, a new class of safe, nonaddicting, mechan...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:The American journal of medicine 2024-12
1. Verfasser: Spector, Reynold
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title The American journal of medicine
container_volume
creator Spector, Reynold
description Thirty percent of Americans report insomnia. After eliminating obvious causes, the best therapy for insomnia is cognitive behavioral therapy, but this is not widely available. However, all the known oral sleeping aides are generally unsatisfactory. Recently, a new class of safe, nonaddicting, mechanism-based hypocretin blockers have been developed. Herein we review the information not only for insomnia but also for narcolepsy.
doi_str_mv 10.1016/j.amjmed.2024.11.019
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_3146517810</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0002934324007745</els_id><sourcerecordid>3146517810</sourcerecordid><originalsourceid>FETCH-LOGICAL-c1563-fafcde88f68857e7c5b29994800edfce12eb06493a0256353d3917e6451a288a3</originalsourceid><addsrcrecordid>eNp9kN9LwzAQx4Mobk7_A5E-iS-tuaRJkxdBhj8GAwfO55Cl15HSrjPZFP97OzpffTqO-3zvuA8h10AzoCDv68y2dYtlxijLM4CMgj4hYxBCpAVIdkrGlFKWap7zEbmIse5bqoU8JyOuJQeZ8zG5XYRuHTDGZNl921AmdpPMSrRN8t4gbv1mnSx801ySs8o2Ea-OdUI-np-W09d0_vYymz7OUwdC8rSylStRqUoqJQosnFgxrXWuKMWycggMV1TmmlvKel7wkmsoUOYCLFPK8gm5G_ZuQ_e5x7gzrY8Om8ZusNtHwyGXAgoFtEfzAXWhizFgZbbBtzb8GKDmYMjUZjBkDoYMgOkN9bGb44X96jD7C_0p6YGHAcD-zy-PwUTnceOw9AHdzpSd___CL1HEdic</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>3146517810</pqid></control><display><type>article</type><title>Progress Toward an Ideal Sleeping Pill</title><source>Elsevier ScienceDirect Journals Complete - AutoHoldings</source><creator>Spector, Reynold</creator><creatorcontrib>Spector, Reynold</creatorcontrib><description>Thirty percent of Americans report insomnia. After eliminating obvious causes, the best therapy for insomnia is cognitive behavioral therapy, but this is not widely available. However, all the known oral sleeping aides are generally unsatisfactory. Recently, a new class of safe, nonaddicting, mechanism-based hypocretin blockers have been developed. Herein we review the information not only for insomnia but also for narcolepsy.</description><identifier>ISSN: 0002-9343</identifier><identifier>ISSN: 1555-7162</identifier><identifier>EISSN: 1555-7162</identifier><identifier>DOI: 10.1016/j.amjmed.2024.11.019</identifier><identifier>PMID: 39631643</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Hypocretinss ; Insomnia ; Narcloepsy ; Orexin</subject><ispartof>The American journal of medicine, 2024-12</ispartof><rights>2024 Elsevier Inc.</rights><rights>Copyright © 2024 Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c1563-fafcde88f68857e7c5b29994800edfce12eb06493a0256353d3917e6451a288a3</cites><orcidid>0000-0001-7892-9555</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.amjmed.2024.11.019$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,778,782,3539,27911,27912,45982</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/39631643$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Spector, Reynold</creatorcontrib><title>Progress Toward an Ideal Sleeping Pill</title><title>The American journal of medicine</title><addtitle>Am J Med</addtitle><description>Thirty percent of Americans report insomnia. After eliminating obvious causes, the best therapy for insomnia is cognitive behavioral therapy, but this is not widely available. However, all the known oral sleeping aides are generally unsatisfactory. Recently, a new class of safe, nonaddicting, mechanism-based hypocretin blockers have been developed. Herein we review the information not only for insomnia but also for narcolepsy.</description><subject>Hypocretinss</subject><subject>Insomnia</subject><subject>Narcloepsy</subject><subject>Orexin</subject><issn>0002-9343</issn><issn>1555-7162</issn><issn>1555-7162</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><recordid>eNp9kN9LwzAQx4Mobk7_A5E-iS-tuaRJkxdBhj8GAwfO55Cl15HSrjPZFP97OzpffTqO-3zvuA8h10AzoCDv68y2dYtlxijLM4CMgj4hYxBCpAVIdkrGlFKWap7zEbmIse5bqoU8JyOuJQeZ8zG5XYRuHTDGZNl921AmdpPMSrRN8t4gbv1mnSx801ySs8o2Ea-OdUI-np-W09d0_vYymz7OUwdC8rSylStRqUoqJQosnFgxrXWuKMWycggMV1TmmlvKel7wkmsoUOYCLFPK8gm5G_ZuQ_e5x7gzrY8Om8ZusNtHwyGXAgoFtEfzAXWhizFgZbbBtzb8GKDmYMjUZjBkDoYMgOkN9bGb44X96jD7C_0p6YGHAcD-zy-PwUTnceOw9AHdzpSd___CL1HEdic</recordid><startdate>20241202</startdate><enddate>20241202</enddate><creator>Spector, Reynold</creator><general>Elsevier Inc</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0001-7892-9555</orcidid></search><sort><creationdate>20241202</creationdate><title>Progress Toward an Ideal Sleeping Pill</title><author>Spector, Reynold</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c1563-fafcde88f68857e7c5b29994800edfce12eb06493a0256353d3917e6451a288a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Hypocretinss</topic><topic>Insomnia</topic><topic>Narcloepsy</topic><topic>Orexin</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Spector, Reynold</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The American journal of medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Spector, Reynold</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Progress Toward an Ideal Sleeping Pill</atitle><jtitle>The American journal of medicine</jtitle><addtitle>Am J Med</addtitle><date>2024-12-02</date><risdate>2024</risdate><issn>0002-9343</issn><issn>1555-7162</issn><eissn>1555-7162</eissn><abstract>Thirty percent of Americans report insomnia. After eliminating obvious causes, the best therapy for insomnia is cognitive behavioral therapy, but this is not widely available. However, all the known oral sleeping aides are generally unsatisfactory. Recently, a new class of safe, nonaddicting, mechanism-based hypocretin blockers have been developed. Herein we review the information not only for insomnia but also for narcolepsy.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>39631643</pmid><doi>10.1016/j.amjmed.2024.11.019</doi><orcidid>https://orcid.org/0000-0001-7892-9555</orcidid></addata></record>
fulltext fulltext
identifier ISSN: 0002-9343
ispartof The American journal of medicine, 2024-12
issn 0002-9343
1555-7162
1555-7162
language eng
recordid cdi_proquest_miscellaneous_3146517810
source Elsevier ScienceDirect Journals Complete - AutoHoldings
subjects Hypocretinss
Insomnia
Narcloepsy
Orexin
title Progress Toward an Ideal Sleeping Pill
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-15T13%3A21%3A20IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Progress%20Toward%20an%20Ideal%20Sleeping%20Pill&rft.jtitle=The%20American%20journal%20of%20medicine&rft.au=Spector,%20Reynold&rft.date=2024-12-02&rft.issn=0002-9343&rft.eissn=1555-7162&rft_id=info:doi/10.1016/j.amjmed.2024.11.019&rft_dat=%3Cproquest_cross%3E3146517810%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=3146517810&rft_id=info:pmid/39631643&rft_els_id=S0002934324007745&rfr_iscdi=true