Capture of Totipotency in Mouse Embryonic Stem Cells in the Absence of Pdzk1

Totipotent cells can differentiate into three lineages: the epiblast, primitive endoderm, and trophectoderm. Naturally, only early fertilized embryos possess totipotency, and they lose this ability as they develop. The expansion of stem cell differentiation potential has been a hot topic in developm...

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Veröffentlicht in:Advanced science 2024-12, p.e2408852
Hauptverfasser: Zhang, Wenhao, Zhao, Yiding, Yang, Zhe, Yan, Jing, Wang, Haisong, Nie, Shaochen, Jia, Qingshen, Ding, Dan, Tong, Chao, Zhang, Xiao-Ou, Gao, Qian, Shuai, Ling
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Sprache:eng
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