Electrochemical immunosensing of Crohn’s disease biomarkers using diazonium salt-grafted crystalline nanocellulose/carbon nanotube-modified electrodes

The first dual immunosensor is reported for the determination of IL-12 and IL-23, two relevant biomarkers of Crohn’s disease (CD). The strategy relies on the selective capture of the targets by the respective antibodies which were covalently immobilized onto SPCEs modified with crystalline nanocellu...

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Veröffentlicht in:	Mikrochimica acta (1966) 2025-01, Vol.192 (1), p.4, Article 4
Hauptverfasser:	García-Rodrigo, Lorena, Ramos-López, Claudia, Sánchez-Tirado, Esther, Agüí, Lourdes, González-Cortés, Araceli, Yáñez-Sedeño, Paloma, Pingarrón, José M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical Chemistry Antibodies Antibodies, Immobilized - immunology Biomarkers Biomarkers - analysis Biomarkers - blood Biosensing Techniques - methods Cellulose - chemistry Characterization and Evaluation of Materials Chemistry Chemistry and Materials Science Conjugation Crohn Disease - diagnosis Crohn's disease Diazonium Compounds - chemistry Electrical measurement Electrochemical Techniques - instrumentation Electrochemical Techniques - methods Electrodes Feces Feces - chemistry Humans Hydrogen peroxide Immunoassay - methods Immunosensors Interleukin-12 - blood Interleukin-12 - immunology Interleukin-23 - blood Interleukin-23 - immunology Limit of Detection Microengineering Multi wall carbon nanotubes Nanochemistry Nanomaterials Nanotechnology Nanotubes, Carbon - chemistry
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